Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, Charlestown, MA, USA.
Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Ann Neurol. 2023 Nov;94(5):919-924. doi: 10.1002/ana.26740. Epub 2023 Aug 9.
We developed and validated an abbreviated version of the Coma Recovery Scale-Revised (CRS-R), the CRS-R For Accelerated Standardized Testing (CRSR-FAST), to detect conscious awareness in patients with severe traumatic brain injury in the intensive care unit. In 45 consecutively enrolled patients, CRSR-FAST administration time was approximately one-third of the full-length CRS-R (mean [SD] 6.5 [3.3] vs 20.1 [7.2] minutes, p < 0.0001). Concurrent validity (simple kappa 0.68), test-retest (Mak's ρ = 0.76), and interrater (Mak's ρ = 0.91) reliability were substantial. Sensitivity, specificity, and accuracy for detecting consciousness were 81%, 89%, and 84%, respectively. The CRSR-FAST facilitates serial assessment of consciousness, which is essential for diagnostic and prognostic accuracy. ANN NEUROL 2023;94:919-924.
我们开发并验证了简化版昏迷恢复量表修订版(CRS-R),即昏迷恢复量表快速版(CRSR-FAST),用于检测重症监护病房中严重创伤性脑损伤患者的意识。在连续入组的 45 名患者中,CRSR-FAST 的管理时间约为完整 CRS-R 的三分之一(平均[标准差]6.5[3.3]分钟 vs 20.1[7.2]分钟,p<0.0001)。同时效度(简单kappa 0.68)、测试-再测试(Mak's ρ=0.76)和观察者间信度(Mak's ρ=0.91)均较高。检测意识的敏感性、特异性和准确性分别为 81%、89%和 84%。CRSR-FAST 有助于进行意识的连续评估,这对于诊断和预后的准确性至关重要。ANN NEUROL 2023;94:919-924.