Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, Spain.
Trop Med Int Health. 2023 Sep;28(9):689-698. doi: 10.1111/tmi.13915. Epub 2023 Jul 24.
To analyse acute Chagas disease (CD) outbreaks through a qualitative systematic review and discuss the determinants for its prevention and control.
Review of studies in which clinical cases of oral transmission were confirmed by parasitological and/or serological tests that included an epidemiological investigation of sources of infection, vectors and reservoirs.
Thirty-two outbreaks (1965-2022) were analysed. The main foods involved in oral transmission outbreaks are homemade fruit juices. Different species of vectors were identified. Reservoirs were mainly dogs, rodents and large American opossums (didelphids).
Under a One Health approach, environmental changes are one of the factors responsible of the rise of oral transmission of CD. Entomological surveillance of vectors and control of the changes in wild and domestic reservoirs and reinforcement of hygiene measures around food in domestic and commercial sites are needed.
通过定性系统评价分析急性恰加斯病（CD）暴发，并讨论其预防和控制的决定因素。
对经寄生虫学和/或血清学检测证实有经口传播临床病例的研究进行回顾，其中包括对感染源、媒介和储存宿主的流行病学调查。
分析了 32 起暴发（1965-2022 年）。经口传播暴发中涉及的主要食物是自制果汁。确定了不同种类的媒介。储存宿主主要是狗、啮齿动物和大型美洲负鼠（有袋目）。
在“同一健康”方法下，环境变化是导致 CD 经口传播增加的因素之一。需要对媒介进行昆虫学监测，并控制野生和家养储存宿主的变化，加强家庭和商业场所食品周边的卫生措施。
