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揭示社区中购买非处方短效β-激动剂(SABA)患者的鼻炎负担。

Uncovering the Burden of Rhinitis in Patients Purchasing Nonprescription Short-Acting β-Agonist (SABA) in the Community.

作者信息

Alamyar Sara, Azzi Elizabeth, Srour-Alphonse Pamela, House Rachel, Cvetkovski Biljana, Kritikos Vicky, Bosnic-Anticevich Sinthia

机构信息

Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia.

Quality Use of Respiratory Medicine Group, Woolcock Institute of Medical Research, The University of Sydney, Sydney, NSW 2006, Australia.

出版信息

Pharmacy (Basel). 2023 Jul 10;11(4):115. doi: 10.3390/pharmacy11040115.

Abstract

Asthma and rhinitis are common comorbidities that amplify the burden of each disease. They are both characterized by poor symptom control, low adherence to clinical management guidelines, and high levels of patient self-management. Therefore, this study aims to investigate the prevalence of self-reported rhinitis symptoms in people with asthma purchasing Short-Acting Beta Agonist (SABA) reliever medication from a community pharmacy and compare the medication-related behavioral characteristics among those who self-report rhinitis symptoms and those who do not. Data were analyzed from 333 people with asthma who visited one of eighteen community pharmacies in New South Wales from 2017-2018 to purchase SABA and completed a self-administered questionnaire. Participants who reported rhinitis symptoms (71%), compared to those who did not, were significantly more likely to have coexisting gastroesophageal reflux disease (GERD), overuse SABA, and experience side effects. They may have been prescribed daily preventer medication but forget to take it, and worry about its side effects. They were also more likely to experience moderate-to-severe rhinitis (74.0%), inaccurately perceive their asthma as well-controlled (50.0% self-determined vs. 14.8% clinical-guideline defined), and unlikely to use rhinitis medications (26.2%) or daily preventer medication (26.7%). These findings enhance our understanding of this cohort and allow us to identify interventions to improve patient outcomes.

摘要

哮喘和鼻炎是常见的合并症,会加重每种疾病的负担。它们的共同特点是症状控制不佳、对临床管理指南的依从性低以及患者自我管理水平高。因此,本研究旨在调查从社区药房购买短效β受体激动剂(SABA)缓解药物的哮喘患者中自我报告的鼻炎症状的患病率,并比较自我报告有鼻炎症状和没有鼻炎症状的患者在药物相关行为特征方面的差异。对2017年至2018年期间到新南威尔士州18家社区药房之一购买SABA并完成自我调查问卷的333名哮喘患者的数据进行了分析。与未报告鼻炎症状的参与者相比,报告有鼻炎症状的参与者(71%)同时患有胃食管反流病(GERD)、过度使用SABA以及出现副作用的可能性显著更高。他们可能已被开具每日预防性药物,但却忘记服用,并担心其副作用。他们也更有可能经历中重度鼻炎(74.0%),错误地认为自己的哮喘得到了良好控制(50.0%自我认定 vs. 临床指南定义的14.8%),并且不太可能使用鼻炎药物(使用鼻炎药物的比例为26.2%)或每日预防性药物(使用每日预防性药物的比例为26.7%)。这些发现增进了我们对这一队列的了解,并使我们能够确定改善患者治疗效果的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fd7/10366934/af3f4b3555df/pharmacy-11-00115-g0A1a.jpg

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