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用于检测传染病和抗菌药物耐药性的比色测试的最新进展

Recent Advances in Colorimetric Tests for the Detection of Infectious Diseases and Antimicrobial Resistance.

作者信息

Celik Cagla, Kalin Gamze, Cetinkaya Zekeriya, Ildiz Nilay, Ocsoy Ismail

机构信息

Pharmacy Services Program, Vocational School of Health Services, Hitit University, Corum 19000, Turkey.

Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erciyes University, Kayseri 38039, Turkey.

出版信息

Diagnostics (Basel). 2023 Jul 20;13(14):2427. doi: 10.3390/diagnostics13142427.

Abstract

Diagnosis of infection-causing microorganisms with sensitive, rapid, selective and economical diagnostic tests is critical to start the right treatment. With these tests, the spread of infections can be prevented. In addition to that, the detection of antimicrobial resistance also makes a significant contribution to public health. In recent years, different types of diagnostic tests have been developed as alternatives to traditional diagnostic tests used in clinics. In particular, colorimetric tests, which minimize the need for an instrument, have advantages owing to their cost effectiveness, rapid response and naked-eye detection and practical use. In this review, we especially focused on pH indicators and nanomaterial-based colorimetric tests in detection of infection-causing microorganisms and antimicrobial resistance.

摘要

使用灵敏、快速、有选择性且经济的诊断测试来诊断引起感染的微生物对于开展正确治疗至关重要。通过这些测试,可以预防感染的传播。此外,对抗菌素耐药性的检测也对公共卫生做出了重大贡献。近年来,已开发出不同类型的诊断测试,作为临床中使用的传统诊断测试的替代方法。特别是比色测试,其对仪器的需求降至最低,因其成本效益高、响应迅速、可裸眼检测及实际应用而具有优势。在本综述中,我们特别关注了用于检测引起感染的微生物和抗菌素耐药性的pH指示剂和基于纳米材料的比色测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b151/10377832/598efa041d95/diagnostics-13-02427-g002.jpg

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