Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, PA, Brazil.
Laboratory of Medical Entomology, Stadual University of Maranhão, Caxias 65604-380, MA, Brazil.
Genes (Basel). 2023 Jul 14;14(7):1443. doi: 10.3390/genes14071443.
A wide diversity of pathogenic mosquito-borne viruses circulate in the Brazilian Amazon, and the intense deforestation can contribute to the spread of these viruses. In this context, this study aimed to investigate the viral diversity in mosquitoes of the genera , , and from a transition area between the Amazon, Cerrado, and Caatinga biomes in Brazil. Metagenomic high-throughput sequencing was used to characterize the virome of 20 mosquito pools. A total of 15 virus-like genomes were identified, comprising species genomically close to insect-specific viruses of the families , , , , , and and species of plant viruses of the families , , and . However, sequences of viruses associated with human and animal diseases were not detected. Most of the recovered genomes were divergent from those previously described. These findings reveal that there are a large number of unknown viruses to be explored in the middle-north of Brazil.
巴西亚马逊地区存在着广泛多样的致病性虫媒病毒，而强烈的森林砍伐可能会导致这些病毒的传播。在这种背景下，本研究旨在调查巴西亚马逊、塞拉多和卡廷加生物群落过渡区属 、 、 和 蚊子中的病毒多样性。使用宏基因组高通量测序来描述 20 个蚊子池的病毒组。总共鉴定出 15 种类似病毒的基因组，包括与科的昆虫特异性病毒、科、科、科和科以及科和科的植物病毒密切相关的种。然而，没有检测到与人类和动物疾病相关的病毒序列。大多数回收的基因组与先前描述的基因组有很大的差异。这些发现表明，在巴西中北部地区还有大量未知病毒有待探索。
