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通过下一代测序技术在巴西 和 蚊虫中检测到湖北类似 Reo 病毒 7 的 RNA 依赖性 RNA 聚合酶。

Detection of RNA-Dependent RNA Polymerase of Hubei Reo-Like Virus 7 by Next-Generation Sequencing in and Mosquitoes from Brazil.

机构信息

Institute f Biological Sciences, Federal University of Pará, Av. Augusto Correa01, CEP 66075-000 Belém, Pará, Brazil.

Laboratório de Vetores, Superintendência de Vigilância em Saúde do Amapá, Rua Tancredo Neves, 1.118, CEP 68905-230 Macapá, AP, Brazil.

出版信息

Viruses. 2019 Feb 10;11(2):147. doi: 10.3390/v11020147.

DOI:10.3390/v11020147
PMID:30744159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6410231/
Abstract

Advancements in next-generation sequencing and bioinformatics have expanded our knowledge of the diversity of viruses (pathogens and non-pathogens) harbored by mosquitoes. Hubei reo-like virus 7 (HRLV 7) was recently detected by the virome analysis of fecal samples from migratory birds in Australia. We now report the detection of RNA-dependent RNA polymerase sequences of HRLV 7 in pools of and mosquitoes species from the Brazilian Amazon forest. Phylogenetic inferences indicated that all HRLV 7 strains fall within the same independent clade. In addition, HRLV 7 shared a close ancestral lineage with the genus of the Reoviridae family. Our findings indicate that HRLV 7 is present in two species of mosquitoes.

摘要

下一代测序和生物信息学的进步扩展了我们对蚊子携带的病毒(病原体和非病原体)多样性的认识。最近,通过对澳大利亚候鸟粪便样本的病毒组分析,发现了湖北雷样病毒 7(HRLV 7)。我们现在报告了在来自巴西亚马逊森林的 和 蚊子种类的样本中检测到 HRLV 7 的 RNA 依赖性 RNA 聚合酶序列。系统发育推断表明,所有 HRLV 7 株都属于同一独立分支。此外,HRLV 7 与呼肠孤病毒科的 属有密切的亲缘关系。我们的研究结果表明,HRLV 7 存在于两种蚊子中。

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