荧光纳米探针在食品安全检测中的最新进展
Recent Advances in Fluorescent Nanoprobes for Food Safety Detection.
机构信息
Department of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.
Institute of Analysis and Testing, Beijing Academy of Science and Technology (Beijing Center for Physical & Chemical Analysis), Beijing 100089, China.
出版信息
Molecules. 2023 Jul 24;28(14):5604. doi: 10.3390/molecules28145604.
Fluorescent nanoprobes show similar fluorescence properties to traditional organic dyes, but the addition of nanotechnology accurately controls the size, shape, chemical composition, and surface chemistry of the nanoprobes with unique characteristics and properties, such as bright luminescence, high photostability, and strong biocompatibility. For example, modifying aptamers or antibodies on a fluorescent nanoprobe provides high selectivity and specificity for different objects to be tested. Fluorescence intensity, life, and other parameters of targets can be changed by different sensing mechanisms based on the unique structural and optical characteristics of fluorescent nanoprobes. What's more, the detection of fluorescent nanoprobes is cost-saving, simple, and offers great advantages in rapid food detection. Sensing mechanisms of fluorescent nanoprobes were introduced in this paper, focusing on the application progress in pesticide residues, veterinary drug residues, heavy metals, microbes, mycotoxins, and other substances in food safety detection in recent years. A brief outlook for future development was provided as well.
荧光纳米探针具有与传统有机染料相似的荧光性质，但纳米技术的加入可以精确控制纳米探针的尺寸、形状、化学成分和表面化学性质，赋予其独特的特性和性能，如明亮的发光、高光稳定性和强生物相容性。例如，在荧光纳米探针上修饰适体或抗体，可以为不同待检测的对象提供高选择性和特异性。基于荧光纳米探针独特的结构和光学特性，可以通过不同的传感机制改变目标的荧光强度、寿命和其他参数。此外，荧光纳米探针的检测具有节省成本、简单的优点，在快速食品检测方面具有很大的优势。本文介绍了荧光纳米探针的传感机制，重点介绍了近年来在食品安全检测中用于检测农药残留、兽药残留、重金属、微生物、真菌毒素等物质的应用进展。并对未来的发展进行了简要展望。
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