基于荧光偏振的生物传感器中使用的纳米材料。
Nanomaterials Used in Fluorescence Polarization Based Biosensors.
机构信息
Department of Chemical and Biochemical Engineering, University of Western Ontario, London, ON N6A 5B9, Canada.
School of Biomedical Engineering, University of Western Ontario, London, ON N6A 5B9, Canada.
出版信息
Int J Mol Sci. 2022 Aug 3;23(15):8625. doi: 10.3390/ijms23158625.
Fluorescence polarization (FP) has been applied in detecting chemicals and biomolecules for early-stage diagnosis, food safety analyses, and environmental monitoring. Compared to organic dyes, inorganic nanomaterials such as quantum dots have special fluorescence properties that can enhance the photostability of FP-based biosensing. In addition, nanomaterials, such as metallic nanoparticles, can be used as signal amplifiers to increase fluorescence polarization. In this review paper, different types of nanomaterials used in in FP-based biosensors have been reviewed. The role of each type of nanomaterial, acting as a fluorescent element and/or the signal amplifier, has been discussed. In addition, the advantages of FP-based biosensing systems have been discussed and compared with other fluorescence-based techniques. The integration of nanomaterials and FP techniques allows biosensors to quickly detect analytes in a sensitive and cost-effective manner and positively impact a variety of different fields including early-stage diagnoses.
荧光偏振（FP）已被应用于化学物质和生物分子的检测，用于早期诊断、食品安全分析和环境监测。与有机染料相比，量子点等无机纳米材料具有特殊的荧光特性，可以增强基于 FP 的生物传感的光稳定性。此外，纳米材料（如金属纳米粒子）可用作信号放大器来增加荧光偏振。在这篇综述论文中，综述了用于基于 FP 的生物传感器的不同类型的纳米材料。讨论了每种类型的纳米材料作为荧光元件和/或信号放大器的作用。此外，还讨论了基于 FP 的生物传感系统的优势，并与其他基于荧光的技术进行了比较。纳米材料和 FP 技术的结合使得生物传感器能够以灵敏且具有成本效益的方式快速检测分析物，并对包括早期诊断在内的各种不同领域产生积极影响。
Zotero 插件