利用微生物组信息进行动物遗传改良。

Leveraging microbiome information for animal genetic improvement.

机构信息

Programa de Doctorado en Ciencias Silvoagropecuarias y Veterinarias, Campus Sur Universidad de Chile, Santa Rosa 11315, La Pintana, Santiago, Chile; Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile; Institut de Biologie Intégrative et des Systèmes, Université Laval, Québec, Canada.

Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile.

出版信息

Trends Genet. 2023 Oct;39(10):721-723. doi: 10.1016/j.tig.2023.07.004. Epub 2023 Jul 27.

DOI:10.1016/j.tig.2023.07.004

PMID:37516623

Abstract

There is growing evidence that the microbiome influences host phenotypic variation. Incorporating information about the holobiont - the host and its microbiome - into genomic prediction models may accelerate genetic improvements in farmed animal populations. Importantly, these models must account for the indirect effects of the host genome on microbiome-mediated phenotypes.

摘要

越来越多的证据表明微生物组会影响宿主表型的变异。将宿主及其微生物组的整体信息纳入基因组预测模型中，可能会加速养殖动物群体的遗传改良。重要的是，这些模型必须考虑宿主基因组对微生物介导的表型的间接影响。