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本文引用的文献

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Visual-spatial processing impairment in the occipital-frontal connectivity network at early stages of Alzheimer's disease.阿尔茨海默病早期枕额连接网络中的视觉空间处理障碍。
Front Aging Neurosci. 2023 Feb 9;15:1097577. doi: 10.3389/fnagi.2023.1097577. eCollection 2023.
2
Locations of objects are better remembered than their identities in naturalistic scenes: An eye-tracking experiment in mild cognitive impairment.在自然场景中,物体的位置比其身份更容易被记住:轻度认知障碍的眼动实验。
Neuropsychology. 2023 Oct;37(7):741-752. doi: 10.1037/neu0000869. Epub 2022 Nov 10.
3
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2019.1990 - 2019年全球、区域及国家层面阿尔茨海默病和其他痴呆症的负担
Front Aging Neurosci. 2022 Oct 10;14:937486. doi: 10.3389/fnagi.2022.937486. eCollection 2022.
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Social cognition deficits and biometric signatures in the behavioural variant of Alzheimer's disease.行为变异型阿尔茨海默病的社会认知缺陷和生物标志物。
Brain. 2023 May 2;146(5):2163-2174. doi: 10.1093/brain/awac382.
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A novel deep learning approach for diagnosing Alzheimer's disease based on eye-tracking data.一种基于眼动追踪数据诊断阿尔茨海默病的新型深度学习方法。
Front Hum Neurosci. 2022 Sep 9;16:972773. doi: 10.3389/fnhum.2022.972773. eCollection 2022.
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The Effects of Normal Aging, Subjective Cognitive Decline, Mild Cognitive Impairment, or Alzheimer's Disease on Visual Search.正常衰老、主观认知下降、轻度认知障碍或阿尔茨海默病对视觉搜索的影响。
J Alzheimers Dis. 2022;88(4):1639-1650. doi: 10.3233/JAD-220209.
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Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer's Disease.扫视缩短可作为一种易于使用的生物标志物,用于检测阿尔茨海默病的风险。
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关注痴呆症:眼球运动与认知能力下降之间的相互作用概述。

Eyes on dementia: an overview of the interplay between eye movements and cognitive decline.

机构信息

Department of Neuroscience, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania.

出版信息

J Med Life. 2023 May;16(5):642-662. doi: 10.25122/jml-2023-0217.

DOI:10.25122/jml-2023-0217
PMID:37520470
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10375353/
Abstract

The economic and disease burden of dementia is forecasted to continue increasing. Considering its cognitive effects, timely diagnosis is important in developing a stage-based treatment plan and gathering data to support advocacy efforts and plan healthcare and social services. Eye-tracking technology has emerged as an efficient diagnostic tool in clinical practice and experimental studies. This review aimed to comprehensively analyze various aspects of eye-tracking technology, including pupillometry parameters, eye movements, eye-tracking devices, and neuropsychological tools. We conducted a systematic review retrieving articles published in the last ten years from six databases. Our results provide a complex overview for each included form of dementia/cognitive decline in terms of patient characteristics (age, sex-disaggregated by included pathologies), inclusion and exclusion criteria, devices, and neuropsychological tools. We also summarized findings on fixation stability tasks, saccadic evaluation, pupillometry, scene perception, object recognition, spatial memory, eye-tracking video tasks, and visual search. The eye-tracking method has become more common in cognitive assessments.

摘要

痴呆的经济和疾病负担预计将继续增加。考虑到其认知影响,及时诊断对于制定基于阶段的治疗计划以及收集数据以支持宣传工作、规划医疗保健和社会服务非常重要。眼动追踪技术已成为临床实践和实验研究中的一种有效诊断工具。本综述旨在全面分析眼动追踪技术的各个方面,包括瞳孔测量参数、眼球运动、眼动追踪设备和神经心理学工具。我们从六个数据库中检索了过去十年发表的文章,进行了系统综述。我们的结果为每种形式的痴呆/认知能力下降提供了复杂的概述,包括患者特征(年龄、按包括的病理分类的性别)、纳入和排除标准、设备和神经心理学工具。我们还总结了关于固定稳定性任务、扫视评估、瞳孔测量、场景感知、物体识别、空间记忆、眼动追踪视频任务和视觉搜索的发现。眼动追踪方法在认知评估中变得越来越普遍。