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新冠疫情期间印度扩大肺炎球菌结合疫苗接种的促进因素与障碍:一项定性研究

Enablers and Barriers to the Scaling Up of Pneumococcal Conjugate Vaccine in India During the COVID-19 Pandemic: A Qualitative Study.

作者信息

Hora Rhythm, Ray Arindam, Mehra Rashmi, Priya Tanwi, Koshal Seema Singh, Agrawal Pankaj, Kaur Amanjot, Quadri Syed F, Deb Roy Arup

机构信息

John Snow India, New Delhi, India.

Bill and Melinda Gates Foundation, New Delhi, India.

出版信息

Health Serv Insights. 2023 Jul 31;16:11786329231189407. doi: 10.1177/11786329231189407. eCollection 2023.

Abstract

BACKGROUND

Pneumonia is one of the leading causes of death in under-5 children in India. This led the Ministry of Health & Family Welfare (MoHFW) in India to decide for the nationwide roll-out of the Pneumococcal Conjugate Vaccine (PCV). However, the introduction of PCV became more complex in the face of unprecedented challenges set forth by the COVID-19 pandemic. The study aims to assess enablers and barriers to the introduction of PCV in India during the pandemic.

METHODOLOGY

Qualitative research approach involving key-informant interviews from John Snow India (JSI), the lead technical agency that supported MoHFW in the PCV expansion was employed to delineate the enablers and barriers. Principle of saturation was employed to derive the sample size. Thematic analysis using inductive approach was based on the modified World Health Organization (WHO) framework for new vaccine introduction impact on the Immunization and Health Systems, using NVIVO 12 qualitative data analysis software.

RESULTS

A total of 11 key informants (4 national-level program managers and 7 state technical officers) were telephonically interviewed. The study found social acceptance, lower cost of the vaccine, and intensive communication activities as potential enablers. Other enablers for PCV introduction included a robust vaccine supply-chain system, ample cold-chain space availability, and strong political commitment, despite the ongoing second wave. Further, the identified barriers included poor physical access, insufficient social mobilization, and limited advocacy along with a stretched workforce.

CONCLUSION

The study delineated several enablers and barriers to introducing PCV in the country during the pandemic. The existing barriers in the PCV roll-out prompted the need to address these gaps, making key program-based recommendations to improve future new vaccine introductions during the pandemic.

摘要

背景

肺炎是印度5岁以下儿童的主要死因之一。这促使印度卫生与家庭福利部决定在全国范围内推广肺炎球菌结合疫苗(PCV)。然而,面对新冠疫情带来的前所未有的挑战,PCV的引入变得更加复杂。本研究旨在评估疫情期间印度引入PCV的推动因素和障碍。

方法

采用定性研究方法,对支持卫生与家庭福利部进行PCV推广的主要技术机构约翰·斯诺印度公司(JSI)的关键信息提供者进行访谈,以确定推动因素和障碍。采用饱和原则确定样本量。使用归纳法进行主题分析,其基于经修改的世界卫生组织(WHO)新疫苗引入对免疫和卫生系统影响的框架,使用NVIVO 12定性数据分析软件。

结果

共对11名关键信息提供者(4名国家级项目经理和7名州技术官员)进行了电话访谈。研究发现社会接受度、疫苗成本降低以及密集的宣传活动是潜在的推动因素。尽管第二波疫情仍在持续,但引入PCV的其他推动因素包括强大的疫苗供应链系统、充足的冷链空间以及坚定的政治承诺。此外,已确定的障碍包括实际获取不便、社会动员不足、宣传有限以及工作人员紧张。

结论

该研究明确了疫情期间该国引入PCV的若干推动因素和障碍。PCV推广中存在的现有障碍促使有必要弥补这些差距,基于关键项目提出建议,以改善疫情期间未来新疫苗的引入。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f915/10392212/7f2396761896/10.1177_11786329231189407-fig1.jpg

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