Novel Cancer Treatment Using Targeted Delivery of Short-Lived Radiologically Activated Nanoparticles.

The goal of our preliminary study is to show that a minimal of overall body toxicity while maximizing the cancer tumor treatment may be achieved in a novel approach where minute amounts of coated nanoparticles may be radiologically activated prior to treatment and "coerce" tumor cells into readily absorb these nanoparticles. This targeted intracytoplasmic delivery of short-lived radiologically activated nanoparticles could provide less "whole-body" radiation dose while delivering a short lived potent tumor localized dose, along with their low toxicity may prove to be another tool in the treatment of diverse cancers.