Nishigori H, Lee J W, Yamauchi Y, Iwatsuru M
Biochem Int. 1986 Jul;13(1):147-53.
When 15-day-old chick embryos were administered 0.25 mumol of hydrocortisone hemisuccinate sodium (HC) the lipid peroxides (LPO) level increased after a lag time and reached about 9-fold of control level at 48 h after the treatment. Thereafter, the amount of LPO decreased to near control level by 72 h. Data obtained by using various steroids indicated that the marked elevation of LPO in blood was related to glucocorticoid effects caused by a high dose administration. The elevation of LPO level in blood was prevented by triple administration of ascorbic acid (20 mumol/egg) at 3, 10 and 20 h after HC treatment.
给15日龄的鸡胚注射0.25微摩尔半琥珀酸氢化可的松钠（HC）后，脂质过氧化物（LPO）水平经过一段延迟时间后升高，在处理后48小时达到对照水平的约9倍。此后，LPO的量在72小时时降至接近对照水平。使用各种类固醇获得的数据表明，血液中LPO的显著升高与高剂量给药引起的糖皮质激素效应有关。在HC处理后3、10和20小时三次注射抗坏血酸（20微摩尔/蛋）可防止血液中LPO水平升高。
