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孕妇饮酒政策与婴儿发病和虐待的关联。

Association of Pregnancy-Specific Alcohol Policies With Infant Morbidities and Maltreatment.

机构信息

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, Oakland.

Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania.

出版信息

JAMA Netw Open. 2023 Aug 1;6(8):e2327138. doi: 10.1001/jamanetworkopen.2023.27138.

Abstract

IMPORTANCE

Research has found associations of pregnancy-specific alcohol policies with increased low birth weight and preterm birth, but associations with other infant outcomes are unknown.

OBJECTIVE

To examine the associations of pregnancy-specific alcohol policies with infant morbidities and maltreatment.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study used outcome data from Merative MarketScan, a national database of private insurance claims. The study cohort included individuals aged 25 to 50 years who gave birth to a singleton between 2006 and 2019 in the US, had been enrolled 1 year before and 1 year after delivery, and could be matched with an infant. Data were analyzed from August 2021 to April 2023.

EXPOSURES

Nine state-level pregnancy-specific alcohol policies obtained from the National Institute on Alcohol Abuse and Alcoholism's Alcohol Policy Information System.

MAIN OUTCOMES AND MEASURES

The primary outcomes were 1 or more infant injuries associated with maltreatment and infant morbidities associated with maternal alcohol consumption within the first year. Logistic regression, adjusting for individual-level and state-level controls, and fixed effects for state, year, state-specific time trends, and SEs clustered by state were used.

RESULTS

A total of 1 432 979 birthing person-infant pairs were included (mean [SD] age of birthing people, 32.2 [4.2] years); 30 157 infants (2.1%) had injuries associated with maltreatment, and 44 461 (3.1%) infants had morbidities associated with alcohol use during pregnancy. The policies of Reporting Requirements for Assessment/Treatment (adjusted odds ratio [aOR], 1.28; 95% CI, 1.08-1.52) and Mandatory Warning Signs (aOR, 1.18; 95% CI, 1.10-1.27) were associated with increased odds of infant injuries but not morbidities. Priority Treatment for Pregnant Women Only was associated with decreased odds of infant injuries (aOR, 0.83; 95% CI, 0.76-0.90) but not infant morbidities. Civil Commitment was associated with increased odds of infant injuries (aOR, 1.26; 95% CI, 1.08-1.48) but decreased odds of infant morbidities (aOR, 0.57; 95% CI, 0.53-0.62). Priority Treatment for Pregnant Women and Women With Children was associated with increased odds of both infant injuries (aOR, 1.12; 95% CI, 1.00-1.25) and infant morbidities (aOR, 1.08; 95% CI, 1.03-1.13). Reporting Requirements for Child Protective Services, Reporting Requirements for Data, Child Abuse/Neglect, and Limits on Criminal Prosecution were not associated with infant injuries or morbidities.

CONCLUSIONS AND RELEVANCE

In this cohort study, most pregnancy-specific alcohol policies were not associated with decreased odds of infant injuries or morbidities. Policy makers should not assume that pregnancy-specific alcohol policies improve infant health.

摘要

重要性

研究发现,特定于妊娠的酒精政策与低出生体重和早产增加有关,但与其他婴儿结局的关联尚不清楚。

目的

研究特定于妊娠的酒精政策与婴儿发病和虐待的关联。

设计、地点和参与者:这是一项回顾性队列研究,使用了 Merative MarketScan 的结果数据,这是一个私人保险索赔的国家数据库。研究队列包括 2006 年至 2019 年在美国分娩的年龄在 25 至 50 岁之间的个体,在分娩前和分娩后 1 年都参加了该研究,并可以与婴儿匹配。数据分析于 2021 年 8 月至 2023 年 4 月进行。

暴露

从国家酒精滥用和酒精中毒研究所的酒精政策信息系统获得的 9 项州级特定于妊娠的酒精政策。

主要结果和措施

主要结果是在婴儿出生后的第一年,与虐待有关的 1 次或多次婴儿受伤和与母亲饮酒有关的婴儿发病。使用逻辑回归,调整个体和州级控制,以及州、年、州特定时间趋势的固定效应和按州聚类的标准误差。

结果

共纳入 1432979 名分娩者-婴儿对(分娩者的平均[SD]年龄为 32.2[4.2]岁);30157 名婴儿(2.1%)有与虐待有关的受伤,44461 名婴儿(3.1%)有与怀孕期间饮酒有关的发病。报告要求评估/治疗(调整后的优势比[OR],1.28;95%CI,1.08-1.52)和强制性警示标志(OR,1.18;95%CI,1.10-1.27)政策与婴儿受伤的几率增加有关,但与发病无关。仅为孕妇提供优先治疗(OR,0.83;95%CI,0.76-0.90)与婴儿受伤的几率降低有关,但与发病无关。强制住院(OR,1.26;95%CI,1.08-1.48)与婴儿受伤的几率增加有关,但与婴儿发病的几率降低(OR,0.57;95%CI,0.53-0.62)有关。仅为孕妇和有子女的妇女提供优先治疗(OR,1.12;95%CI,1.00-1.25)与婴儿受伤(OR,1.08;95%CI,1.03-1.13)和发病的几率增加有关。儿童保护服务报告要求、数据报告要求、儿童虐待/忽视和刑事起诉限制与婴儿受伤或发病无关。

结论和相关性

在这项队列研究中,大多数特定于妊娠的酒精政策与婴儿受伤或发病几率的降低无关。政策制定者不应假设特定于妊娠的酒精政策能改善婴儿健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07b7/10401306/ef7ff4ad4458/jamanetwopen-e2327138-g001.jpg

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