纤维素滤膜上寡核苷酸合成的计算机管理
Computer management of oligonucleotide synthesis on cellulose filters.
作者信息
Tolstoshev C M, Matthes H W, Oudet P
出版信息
Nucleic Acids Res. 1986 Jan 10;14(1):405-15. doi: 10.1093/nar/14.1.405.
Abstract
A computer program, OLIGO, is described which was designed to manage projects involving the synthesis of large numbers of oligonucleotide fragments using cellulose discs as immobilizing support. The program performs the functions of data entry, verification, analysis and modification; the sorting of filters before each step and project status updating after each reaction step; output of the project status at any point and storage of the finalized project data in a permanent reference file.
摘要
介绍了一种计算机程序OLIGO，其设计目的是管理涉及使用纤维素圆盘作为固定支持物合成大量寡核苷酸片段的项目。该程序执行数据输入、验证、分析和修改功能；在每个步骤之前对滤膜进行排序，并在每个反应步骤之后更新项目状态；在任何时候输出项目状态，并将最终的项目数据存储在永久参考文件中。
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