Burnett L
Nucleic Acids Res. 1986 Jan 10;14(1):47-55. doi: 10.1093/nar/14.1.47.
A new strategy for high-resolution nucleotide sequence analysis has been developed. The strategy involves an exhaustive tree-searching algorithm which examines all possible combinations of short regions of sequence alignments, followed by culling of unsuitable sequence relationships. The new algorithm can detect sequence homologies invisible to existing algorithms, and is capable of detecting all possible sequence relationships.
一种用于高分辨率核苷酸序列分析的新策略已被开发出来。该策略涉及一种详尽的树形搜索算法,该算法会检查序列比对短区域的所有可能组合,然后剔除不合适的序列关系。这种新算法能够检测现有算法无法察觉的序列同源性,并且能够检测所有可能的序列关系。