一个用于DNA和蛋白质序列操作与分析的便捷且适应性强的微机环境。
A convenient and adaptable microcomputer environment for DNA and protein sequence manipulation and analysis.
作者信息
Pustell J, Kafatos F C
出版信息
Nucleic Acids Res. 1986 Jan 10;14(1):479-88. doi: 10.1093/nar/14.1.479.
Abstract
We describe the further development of a widely used package of DNA and protein sequence analysis programs for microcomputers (1,2,3). The package now provides a screen oriented user interface, and an enhanced working environment with powerful formatting, disk access, and memory management tools. The new GenBank floppy disk database is supported transparently to the user and a similar version of the NBRF protein database is provided. The programs can use sequence file annotation to automatically annotate printouts and translate or extract specified regions from sequences by name. The sequence comparison programs can now perform a 5000 X 5000 bp analysis in 12 minutes on an IBM PC. A program to locate potential protein coding regions in nucleic acids, a digitizer interface, and other additions are also described.
摘要
我们描述了一个广泛用于微型计算机的DNA和蛋白质序列分析程序包的进一步开发（1,2,3）。该程序包现在提供了一个面向屏幕的用户界面，以及一个具有强大格式化、磁盘访问和内存管理工具的增强工作环境。新的GenBank软盘数据库对用户是透明支持的，并提供了一个类似版本的NBRF蛋白质数据库。这些程序可以使用序列文件注释来自动注释打印输出，并按名称从序列中翻译或提取指定区域。序列比较程序现在可以在IBM个人计算机上12分钟内完成5000×5000碱基对的分析。还描述了一个用于在核酸中定位潜在蛋白质编码区域的程序、一个数字化仪接口以及其他新增功能。
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