Key Laboratory of Spin Electron and Nanomaterials of Anhui Higher Education Institutes, School of Chemistry and Chemical Engineering, Suzhou University, Suzhou, 234000, China.
Key Laboratory of Spin Electron and Nanomaterials of Anhui Higher Education Institutes, School of Chemistry and Chemical Engineering, Suzhou University, Suzhou, 234000, China; School of Chemical Engineering&Technology, China University of Mining and Technology, Xuzhou, 221100, China.
Talanta. 2024 Jan 1;266(Pt 1):125015. doi: 10.1016/j.talanta.2023.125015. Epub 2023 Aug 2.
The directional movement of liquid without exogenous drive can show great potential in portable electrochemical platforms. Herein, we developed a portable electrochemical platform that drove electrolyte flow by surface tension gradient, which can realize collection of electrolyte, flow preconcentration and electrochemical detection of Cu. The induced graphene electrodes (LIG) was fabricated using laser direct writing, and flower cluster shaped ZnO nanorods (FC-ZnONRs) were prepared and modified on LIG, which provided a large amount of space for electrolyte to shuttled between the holes of LIG and ZnO, and increased the electrochemical active sites and electrons transport ability. The effect of surface tension gradients driving fluid flow could accelerate preconcentration, shorten detection time (save 300 s of preconcentration time) and enhance electrochemical responses in synergy with the 3D FC-ZnONRs/LIG. The microfluidic system possessed excellent performance for detection of Cu ranged from 1 μg L to 2100 μg L with a low detection limit (LOD) of 0.0368 μg L and high sensitivity of 0.414 μA (μg L) cm. Additionally, this portable microfluidic system was successfully worn on the skin for analysing Cu in human sweat, and the results showed good consistency with inductively coupled plasma-mass spectrometry (ICP-MS). This novel sensing system provides a sample collection, rapid detection, low cost and easy-to-operate strategy for heavy metal ions analysis in real samples and shows huge application prospects in point-of-care testing.
无外加驱动的液体定向运动在便携电化学平台中具有巨大的应用潜力。在此，我们开发了一种由表面张力梯度驱动电解质流动的便携电化学平台，实现了电解质的收集、流动预浓缩和 Cu 的电化学检测。采用激光直写技术制备了诱导石墨烯电极（LIG），并在 LIG 上制备和修饰了花簇状 ZnO 纳米棒（FC-ZnONRs），为电解质在 LIG 和 ZnO 的孔之间穿梭提供了大量空间，并增加了电化学活性位点和电子传输能力。表面张力梯度驱动流体流动的效果可以加速预浓缩，缩短检测时间（节省 300s 的预浓缩时间），并与 3D FC-ZnONRs/LIG 协同增强电化学响应。微流控系统在 1μg L 至 2100μg L 的范围内对 Cu 的检测具有优异的性能，检测限（LOD）低至 0.0368μg L，灵敏度高，为 0.414μA（μg L）cm。此外，该便携式微流控系统成功佩戴在皮肤上，用于分析人体汗液中的 Cu，与电感耦合等离子体质谱（ICP-MS）的结果具有良好的一致性。这种新型传感系统为实际样品中重金属离子的分析提供了一种样品采集、快速检测、低成本和易于操作的策略，在即时检测中具有巨大的应用前景。
