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The developmental expression of the gene for TFIIIA in Xenopus laevis.

作者信息

Taylor W, Jackson I J, Siegel N, Kumar A, Brown D D

出版信息

Nucleic Acids Res. 1986 Aug 11;14(15):6185-95. doi: 10.1093/nar/14.15.6185.

DOI:10.1093/nar/14.15.6185
PMID:3755818
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC311630/
Abstract

The sequence of the trans-acting positive transcription factor TFIIIA has been deduced by sequencing cDNA and genomic DNA clones. Using DNA from a homozygous diploid animal we show that there is one gene for TFIIIA per haploid genome of X. laevis. Protein sequencing of proteolytic fragments of TFIIIA orients the protein in its interaction with the internal control region (ICR) of the 5S RNA gene. The protein lies along the DNA with its carboxyl terminus at the 5' end of the ICR and its amino terminus at the 3' end. The developmental pattern of TFIIIA and its mRNA during oogenesis and embryogenesis are consistent with the idea that the abundance of TFIIIA plays an essential role in the developmental change in 5S RNA gene expression. The change to almost exclusive somatic 5S RNA gene expression by gastrulation occurs using either the TFIIIA that was synthesized by oocyte and/or TFIIIA synthesized from maternal mRNA.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31b3/311630/7a87b64a2dc4/nar00284-0256-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31b3/311630/7f560348be02/nar00284-0253-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31b3/311630/0d54749bb06a/nar00284-0255-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31b3/311630/7a87b64a2dc4/nar00284-0256-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31b3/311630/7f560348be02/nar00284-0253-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31b3/311630/0d54749bb06a/nar00284-0255-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31b3/311630/7a87b64a2dc4/nar00284-0256-a.jpg

相似文献

1
The developmental expression of the gene for TFIIIA in Xenopus laevis.
Nucleic Acids Res. 1986 Aug 11;14(15):6185-95. doi: 10.1093/nar/14.15.6185.
2
The characterization of the TFIIIA synthesized in somatic cells of Xenopus laevis.非洲爪蟾体细胞中合成的TFIIIA的特性
Genes Dev. 1990 Sep;4(9):1602-10. doi: 10.1101/gad.4.9.1602.
3
Comparison of the sequence and structure of transcription factor IIIA from Bufo americanus and Rana pipiens.美洲蟾蜍和豹蛙转录因子IIIA的序列与结构比较。
Gene. 1992 Oct 21;120(2):197-206. doi: 10.1016/0378-1119(92)90094-6.
4
Identification of a TFIIIA binding site on the 5' flanking region of the TFIIIA gene.在TFIIIA基因5'侧翼区域鉴定出一个TFIIIA结合位点。
Nucleic Acids Res. 1990 May 25;18(10):2923-8. doi: 10.1093/nar/18.10.2923.
5
Regulation of the Xenopus laevis transcription factor IIIA gene during oogenesis and early embryogenesis: negative elements repress the O-TFIIIA promoter in embryonic cells.非洲爪蟾卵母细胞发生和早期胚胎发生过程中III型转录因子A基因的调控:负调控元件抑制胚胎细胞中的O-TFIIIA启动子。
Dev Biol. 1991 Jun;145(2):241-54. doi: 10.1016/0012-1606(91)90123-k.
6
Structural elements in the N-terminal half of transcription factor IIIA required for factor binding to the 5S RNA gene internal control region.转录因子IIIA N端半段中与5S RNA基因内部控制区结合所需的结构元件。
Nucleic Acids Res. 1991 Dec 25;19(24):6871-6. doi: 10.1093/nar/19.24.6871.
7
Two TFIIIA activities regulate expression of the Xenopus 5S RNA gene families.两种TFIIIA活性调节非洲爪蟾5S RNA基因家族的表达。
Genes Dev. 1989 Oct;3(10):1602-12. doi: 10.1101/gad.3.10.1602.
8
Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development.非洲爪蟾5S基因转录因子TFIIIA:cDNA克隆的特性及发育过程中RNA水平的测定
Cell. 1984 Dec;39(3 Pt 2):479-89. doi: 10.1016/0092-8674(84)90455-0.
9
Internal deletion mutants of Xenopus transcription factor IIIA.非洲爪蟾转录因子IIIA的内部缺失突变体
Nucleic Acids Res. 1989 Dec 11;17(23):9861-70. doi: 10.1093/nar/17.23.9861.
10
Dissection of the DNA-binding domain of Xenopus laevis TFIIIA. Quantitative DNase I footprinting analysis of specific complexes between a 5 S RNA gene fragment and N-terminal fragments of TFIIIA containing three, four or five zinc-finger domains.非洲爪蟾TFIIIA DNA结合结构域的剖析。5S RNA基因片段与含有三个、四个或五个锌指结构域的TFIIIA N端片段之间特异性复合物的定量DNase I足迹分析。
J Mol Biol. 1993 Sep 20;233(2):191-202. doi: 10.1006/jmbi.1993.1499.

引用本文的文献

1
Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription.细胞生长和分化依赖性调节 RNA 聚合酶 III 转录。
Cell Cycle. 2010 Sep 15;9(18):3687-99. doi: 10.4161/cc.9.18.13203. Epub 2010 Sep 1.
2
Phosphorylation of Xenopus transcription factor IIIA by an oocyte protein kinase CK2.爪蟾转录因子IIIA被卵母细胞蛋白激酶CK2磷酸化。
Biochem J. 2002 Mar 1;362(Pt 2):375-82. doi: 10.1042/0264-6021:3620375.
3
Xenopus TFIIIA gene transcription is dependent on cis-element positioning and chromatin structure.

本文引用的文献

1
Cytoplasmic regulation of 5S RNA genes in nuclear-transplant embryos.核移植胚胎中5S RNA基因的细胞质调控
EMBO J. 1983;2(9):1613-9. doi: 10.1002/j.1460-2075.1983.tb01632.x.
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A specific transcription factor that can bind either the 5S RNA gene or 5S RNA.一种能与5S RNA基因或5S RNA结合的特异性转录因子。
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4170-4. doi: 10.1073/pnas.77.7.4170.
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Plasmid screening at high colony density.高菌落密度下的质粒筛选
非洲爪蟾TFIIIA基因转录依赖于顺式元件定位和染色质结构。
Mol Cell Biol. 1998 Jul;18(7):3811-8. doi: 10.1128/MCB.18.7.3811.
4
Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex.锌指在DNA识别中的不同作用:一种六指转录因子IIIA复合物的结构
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2938-43. doi: 10.1073/pnas.95.6.2938.
5
Electron microscopic study of crystals of the Xenopus laevis transcription factor IIIA-5S ribosomal RNA complex.非洲爪蟾转录因子IIIA-5S核糖体RNA复合物晶体的电子显微镜研究。
Proc Natl Acad Sci U S A. 1988 Jun;85(11):3802-4. doi: 10.1073/pnas.85.11.3802.
6
Upstream sequences required for transcription of the TFIIIA gene in Xenopus oocytes.非洲爪蟾卵母细胞中TFIIIA基因转录所需的上游序列。
Nucleic Acids Res. 1988 May 11;16(9):3801-14. doi: 10.1093/nar/16.9.3801.
7
Mapping functional regions of transcription factor TFIIIA.绘制转录因子TFIIIA的功能区域图谱。
Mol Cell Biol. 1988 Apr;8(4):1684-96. doi: 10.1128/mcb.8.4.1684-1696.1988.
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Inhibition of host cell RNA polymerase III-mediated transcription by poliovirus: inactivation of specific transcription factors.
Mol Cell Biol. 1987 Nov;7(11):3880-7. doi: 10.1128/mcb.7.11.3880-3887.1987.
9
Presence of multiple species of polypeptides immunologically related to transcription factor TFIIIA in adult Xenopus tissues.成年非洲爪蟾组织中存在多种与转录因子TFIIIA免疫相关的多肽。
Nucleic Acids Res. 1989 Jul 25;17(14):5597-610. doi: 10.1093/nar/17.14.5597.
10
Transcription factor IIIA gene expression in Xenopus oocytes utilizes a transcription factor similar to the major late transcription factor.非洲爪蟾卵母细胞中的转录因子IIIA基因表达利用了一种与主要晚期转录因子相似的转录因子。
Mol Cell Biol. 1989 Nov;9(11):5003-11. doi: 10.1128/mcb.9.11.5003-5011.1989.
Gene. 1980 Jun;10(1):63-7. doi: 10.1016/0378-1119(80)90144-4.
4
High-sensitivity sequencing with a gas-phase sequenator.使用气相测序仪进行高灵敏度测序。
Methods Enzymol. 1983;91:399-413. doi: 10.1016/s0076-6879(83)91038-8.
5
Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis.从聚丙烯酰胺凝胶中分离微克量蛋白质用于氨基酸序列分析。
Methods Enzymol. 1983;91:227-36. doi: 10.1016/s0076-6879(83)91019-4.
6
Domains of the positive transcription factor specific for the Xenopus 5S RNA gene.非洲爪蟾5S RNA基因特异性正转录因子的结构域。
Cell. 1984 Jun;37(2):645-52. doi: 10.1016/0092-8674(84)90396-9.
7
Onset of 5 S RNA gene regulation during Xenopus embryogenesis.非洲爪蟾胚胎发育过程中5S RNA基因调控的起始
Dev Biol. 1983 Sep;99(1):248-57. doi: 10.1016/0012-1606(83)90273-7.
8
Studies on transformation of Escherichia coli with plasmids.大肠杆菌质粒转化的研究。
J Mol Biol. 1983 Jun 5;166(4):557-80. doi: 10.1016/s0022-2836(83)80284-8.
9
Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development.非洲爪蟾5S基因转录因子TFIIIA:cDNA克隆的特性及发育过程中RNA水平的测定
Cell. 1984 Dec;39(3 Pt 2):479-89. doi: 10.1016/0092-8674(84)90455-0.
10
Altered levels of a 5 S gene-specific transcription factor (TFIIIA) during oogenesis and embryonic development of Xenopus laevis.非洲爪蟾卵子发生和胚胎发育过程中5 S基因特异性转录因子(TFIIIA)水平的变化。
J Biol Chem. 1984 Sep 25;259(18):11373-82.