啮齿动物基因组中分散的中度重复DNA的MT家族的分子特征分析。
Molecular characterization of the MT-family of dispersed middle-repetitive DNA in rodent genomes.
作者信息
Heinlein U A, Lange-Sablitzky R, Schaal H, Wille W
出版信息
Nucleic Acids Res. 1986 Aug 26;14(16):6403-16. doi: 10.1093/nar/14.16.6403.
Abstract
We report the consensus sequence of members of a new dispersed middle-repetitive DNA family, MT, which is present in mouse and rat genomes. This family is shown to be as abundant as the described rodent B1 and B2 families. Hybridization experiments with radioactive single-stranded cDNAs from different tissues indicate that MT sequences are more abundantly cotranscribed in parts of the brain than other repetitive families.
摘要
我们报告了一个新的分散性中间重复DNA家族MT成员的共有序列，该家族存在于小鼠和大鼠基因组中。已证明这个家族与已描述的啮齿动物B1和B2家族一样丰富。用来自不同组织的放射性单链cDNA进行的杂交实验表明，MT序列在大脑部分区域的共转录比其他重复家族更为丰富。
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