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西欧 SARS-CoV-2 大流行期间的儿童和学校政策。

Policies on children and schools during the SARS-CoV-2 pandemic in Western Europe.

机构信息

Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Barcelona, Spain.

Infectious Diseases Unit and Emergency Service, Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

出版信息

Front Public Health. 2023 Jul 25;11:1175444. doi: 10.3389/fpubh.2023.1175444. eCollection 2023.

Abstract

During the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mitigation policies for children have been a topic of considerable uncertainty and debate. Although some children have co-morbidities which increase their risk for severe coronavirus disease (COVID-19), and complications such as multisystem inflammatory syndrome and long COVID, most children only get mild COVID-19. On the other hand, consistent evidence shows that mass mitigation measures had enormous adverse impacts on children. A central question can thus be posed: What amount of mitigation should children bear, in response to a disease that is disproportionally affecting older people? In this review, we analyze the distinct child versus adult epidemiology, policies, mitigation trade-offs and outcomes in children in Western Europe. The highly heterogenous European policies applied to children compared to adults did not lead to significant measurable differences in outcomes. Remarkably, the relative epidemiological importance of transmission from school-age children to other age groups remains uncertain, with current evidence suggesting that schools often follow, rather than lead, community transmission. Important learning points for future pandemics are summarized.

摘要

在由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 引起的大流行期间,针对儿童的缓解政策一直是一个相当不确定和有争议的话题。尽管有些儿童有增加其患严重冠状病毒病 (COVID-19) 和并发症(如多系统炎症综合征和长 COVID)风险的合并症,但大多数儿童只患轻度 COVID-19。另一方面,一致的证据表明,大规模缓解措施对儿童产生了巨大的不利影响。因此,可以提出一个核心问题:对于一种不成比例地影响老年人的疾病,儿童应该承受多大程度的缓解?在这篇综述中,我们分析了西欧儿童与成人之间不同的流行病学、政策、缓解权衡和结果。与成年人相比,针对儿童的高度异质欧洲政策并没有导致结果出现显著的可衡量差异。值得注意的是,从学龄儿童向其他年龄组传播的相对流行病学重要性仍不确定,目前的证据表明,学校通常跟随而不是引领社区传播。总结了对未来大流行的重要学习要点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b152/10411527/039050b57cfd/fpubh-11-1175444-g001.jpg

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