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2020 - 2021学年挪威学校中新冠病毒的传播:基于人群登记的队列研究

Transmission of SARS-CoV-2 in Norwegian schools during academic year 2020-21: population wide, register based cohort study.

作者信息

Rotevatn T A, Bergstad Larsen Vilde, Bjordal Johansen Tone, Astrup Elisabeth, Surén Pål, Greve-Isdahl Margrethe, Telle Kjetil Elias

机构信息

Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway.

Division of Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

出版信息

BMJ Med. 2022 Aug 5;1(1):e000026. doi: 10.1136/bmjmed-2021-000026. eCollection 2022.

Abstract

OBJECTIVE

To assess the risk of transmission of SARS-CoV-2 in schools in Norway mainly kept open during the covid-19 pandemic in the academic year 2020-21.

DESIGN

Population wide, register based cohort study.

SETTING

Primary and lower secondary schools in Norway open during the academic year 2020-21, with strict infection prevention and control measures in place, such as organisation of students into smaller cohorts. Contact tracing, quarantine, and isolation were also implemented, and testing of students and staff identified as close contacts.

PARTICIPANTS

All students and educational staff in primary and lower secondary schools in Norway, from August 2020 to June 2021.

MAIN OUTCOME MEASURES

Overall attack rate of SARS-CoV-2 transmission (AR14) was defined as the number of individuals (among students, staff, or both) in the school with covid-19, detected within 14 days of the index case, divided by the number of students and staff members in the school. AR14 to students (attack rates from all index cases to students only) and AR14 to school staff (attack rates from all index cases to staff members only) were also calculated. These measures for student and school staff index cases were also calculated separately to explore variation in AR14 based on the characteristics of the index case.

RESULTS

From August 2020 to June 2021, 4078 index cases were identified; 3220 (79%) students and 858 (21%) school staff. In most (2230 (55%)) schools with an index case, no subsequent individuals with covid-19 were found within 14 days; in 631 (16%) schools, only one more individual with covid-19 within 14 days was found. Overall, AR14 was 0.33% (95% confidence interval 0.32% to 0.33%). When restricting index cases and subsequent individuals with covid-19 to students born in the same year, AR14 to students (0.56-0.78%) was slightly higher.

CONCLUSIONS

Regarding the number of people infected with SARS-CoV-2 among students and staff, these results suggest that schools were not an important setting for transmission of the virus in Norway during the covid-19 pandemic in the academic year 2020-21.

摘要

目的

评估在2020 - 2021学年新冠疫情期间挪威主要保持开放的学校中,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的传播风险。

设计

基于人群登记的队列研究。

背景

2020 - 2021学年挪威开放的中小学,实施了严格的感染预防和控制措施,如将学生分成较小的群组。还实施了接触者追踪、隔离和检疫,并对被确定为密切接触者的学生和教职员工进行检测。

参与者

2020年8月至2021年6月期间挪威中小学的所有学生和教育工作人员。

主要观察指标

SARS-CoV-2传播的总体感染率(AR14)定义为在指示病例出现后14天内学校中确诊感染新冠病毒的个体(学生、教职员工或两者)数量除以学校的学生和教职员工总数。还计算了学生的AR14(仅从所有指示病例到学生的感染率)和学校工作人员的AR14(仅从所有指示病例到工作人员的感染率)。还分别计算了学生和学校工作人员指示病例的这些指标,以根据指示病例的特征探讨AR14的差异。

结果

2020年8月至2021年6月期间,共确定4078例指示病例;其中3220例(79%)为学生,858例(21%)为学校工作人员。在大多数(2230例(55%))有指示病例的学校中,在14天内未发现后续感染新冠病毒的个体;在631例(16%)学校中,在14天内仅发现另外1例感染新冠病毒的个体。总体而言,AR14为0.33%(95%置信区间0.32%至0.33%)。当将指示病例和后续感染新冠病毒的个体限制为同年出生的学生时,学生的AR14(0.56 - 0.78%)略高。

结论

关于学生和教职员工中感染SARS-CoV-2的人数,这些结果表明,在2020 - 2021学年新冠疫情期间,挪威的学校并非病毒传播的重要场所。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d814/9978745/8d3a0f267f2a/bmjmed-2021-000026f01.jpg

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