Amaral Maria Stella Arantes do, Zamberlan-Amorin Nelma Ellen, Mendes Karina Dal Sasso, Bernal Sarah Carolina, Massuda Eduardo Tanaka, Hyppolito Miguel Angelo, Reis Ana Cláudia Mirândola Barbosa
Department of Ophthalmology, Otorhinolaryngology, and Head and Neck Surgery, Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, SP, Brazil.
Centro Especializado de Otorrinolaringologia e Fonoaudiologia (CEOF), Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil.
Int Arch Otorhinolaryngol. 2022 Jul 11;27(3):e518-e527. doi: 10.1055/s-0042-1744172. eCollection 2023 Jul.
The P300 auditory evoked potential is a long-latency cortical potential evoked with auditory stimulation, which provides information on neural mechanisms underlying the central auditory processing. To identify and gather scientific evidence regarding the P300 in adult cochlear implant (CI) users. A total of 87 articles, 20 of which were selected for this study, were identified and exported to the Rayyan search software. Those 20 articles did not propose a homogeneous methodology, which made comparison more difficult. Most articles (60%) in this review compare CI users with typical hearing people, showing prolonged P300 latency in CI users. Among the studies, 35% show that CI users present a smaller P300 amplitude. Another variable is the influence of the kind of stimulus used to elicit P300, which was prolonged in 30% of the studies that used pure tone stimuli, 10% of the studies that used pure tone and speech stimuli, and 60% of the studies that used speech stimuli. This review has contributed with evidence that shows the importance of applying a controlled P300 protocol to diagnose and monitor CI users. Regardless of the stimuli used to elicit P300, we noticed a pattern in the increase in latency and decrease in amplitude in CI users. The user's experience with the CI speech processor over time and the speech test results seem to be related to the P300 latency and amplitude measurements.
P300听觉诱发电位是一种由听觉刺激诱发的长潜伏期皮质电位，它提供了有关中枢听觉处理潜在神经机制的信息。
为了识别和收集关于成年人工耳蜗（CI）使用者P300的科学证据。
共识别出87篇文章，并将其中20篇选入本研究，然后导出到Rayyan搜索软件中。这20篇文章没有提出统一的方法，这使得比较更加困难。本综述中的大多数文章（60%）将CI使用者与听力正常的人进行比较，结果显示CI使用者的P300潜伏期延长。在这些研究中，35%的研究表明CI使用者的P300波幅较小。另一个变量是用于诱发P300的刺激类型的影响，在使用纯音刺激的研究中有30%出现潜伏期延长，在使用纯音和言语刺激的研究中有10%出现潜伏期延长，在使用言语刺激的研究中有60%出现潜伏期延长。
本综述提供了证据，表明应用标准化的P300方案对CI使用者进行诊断和监测具有重要意义。无论用于诱发P300的刺激是什么，我们都注意到CI使用者存在潜伏期延长和波幅降低的模式。使用者使用CI言语处理器的时间长短和言语测试结果似乎与P300潜伏期和波幅测量结果有关。
