Zeeshan Muhammad Abid, Ali Sarmad, Ahmed Ishtiaq, Rehman Aziz Ur, Rafique Muhammad Kamran, Nasir Amar, Khan Aman Ullah, Kashif Muhammad, Mertns-Scholz Katja, Arshad Muhammad Imran, Ehtisham-Ul-Haque Syed, Neubauer Heinrich
Department of Pathobiology (Pathology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, Pakistan.
Department of Clinical Sciences, University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, Pakistan.
Front Vet Sci. 2023 Jul 28;10:1195274. doi: 10.3389/fvets.2023.1195274. eCollection 2023.
Abortion is one of the leading causes of economic losses in the livestock industry worldwide. , , and spp. are the leading cause of late fetal loss in small ruminants. This study determined the seroprevalence of these agents in small ruminants in district Jhang. A total of 385 serum samples were taken from the sheep and goats from different flocks with a history of abortion and subjected to i-ELISA. Further, samples were analysed for liver enzymes and total serum protein using a semi-automated chemistry analyzer. The result of indirect commercial ELISA showed 13.0, 4.2 and 11.2% prevalence for , , and spp., respectively. Values of different serum parameters (ALT, AST, and total protein) of seropositive animals were also determined. There was a significant rise in AST and ALT values of infected animals ( ≤ 0.05). Total protein decreased for all three infections, but a significant drop was noted in positive sheep serum samples. Various risk factors were studied. Binary logistic regression proved a significant role of ticks for coxiellosis and brucellosis. Age, parity, and species did not impact the prevalence of diseases studied.
流产是全球畜牧业经济损失的主要原因之一。[具体病原体名称1]、[具体病原体名称2]和[具体病原体名称3]属是小反刍动物晚期胎儿损失的主要原因。本研究确定了这些病原体在詹格县小反刍动物中的血清流行率。从有流产病史的不同羊群的绵羊和山羊中总共采集了385份血清样本，并进行间接酶联免疫吸附测定（i-ELISA）。此外，使用半自动化学分析仪对样本进行肝酶和总血清蛋白分析。间接商业酶联免疫吸附测定的结果显示，[具体病原体名称1]、[具体病原体名称2]和[具体病原体名称3]属的流行率分别为13.0%、4.2%和11.2%。还测定了血清阳性动物的不同血清参数（谷丙转氨酶、谷草转氨酶和总蛋白）值。感染动物的谷草转氨酶和谷丙转氨酶值显著升高（P≤0.05）。所有三种感染的总蛋白均下降，但在[具体病原体名称1]阳性绵羊血清样本中观察到显著下降。研究了各种风险因素。二元逻辑回归证明蜱虫对柯克斯体病和布鲁氏菌病有显著作用。年龄、胎次和物种对所研究疾病的流行率没有影响。
