胰内脂肪沉积与生活方式因素的关系：一项横断面研究。
Relationships between intra-pancreatic fat deposition and lifestyle factors: a cross-sectional study.
机构信息
Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Department of Lifestyle Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
出版信息
Front Endocrinol (Lausanne). 2023 Jul 27;14:1219579. doi: 10.3389/fendo.2023.1219579. eCollection 2023.
AIMS
The excess deposition of intra-pancreatic fat deposition (IPFD) has been reported to be associated with type 2 diabetes, chronic pancreatitis, and pancreatic ductal adenocarcinoma. In the current study, we aimed to identify a relationship between lifestyle factors and IPFD.
MATERIALS AND METHODS
99 patients admitted to the Osaka University Hospital who had undergone abdominal computed tomography were selected. We evaluated the mean computed tomography values of the pancreas and spleen and then calculated IPFD score. Multiple regression analyses were used to assess the associations between IPFD score and lifestyle factors.
RESULTS
Fast eating speed, late-night eating, and early morning awakening were significantly associated with a high IPFD score after adjusting for age, sex, diabetes status and Body Mass Index (p=0.04, 0.01, 0.01, respectively).
CONCLUSION
The current study has elucidated the significant associations of fast eating speed, late-night eating, and early morning awakening with IPFD.
目的
已有报道称，胰腺内脂肪沉积（IPFD）过多与 2 型糖尿病、慢性胰腺炎和胰腺导管腺癌有关。本研究旨在确定生活方式因素与 IPFD 之间的关系。
材料和方法
选择了在大阪大学医院接受腹部计算机断层扫描的 99 名患者。我们评估了胰腺和脾脏的平均计算机断层扫描值，然后计算了 IPFD 评分。采用多元回归分析评估了 IPFD 评分与生活方式因素之间的关系。
结果
调整年龄、性别、糖尿病状态和体重指数后，进食速度快、深夜进食和清晨早醒与高 IPFD 评分显著相关（分别为 p=0.04、0.01、0.01）。
结论
本研究阐明了进食速度快、深夜进食和清晨早醒与 IPFD 之间的显著关联。
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