Oliveira Cristiana, Sousa Diana, Teixeira José A, Ferreira-Santos Pedro, Botelho Claudia M
CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga, Portugal.
LABBELS-Associate Laboratory, Braga, Portugal.
Front Bioeng Biotechnol. 2023 Jul 27;11:1136077. doi: 10.3389/fbioe.2023.1136077. eCollection 2023.
Skin indicates a person's state of health and is so important that it influences a person's emotional and psychological behavior. In this context, the effective treatment of wounds is a major concern, since several conventional wound healing materials have not been able to provide adequate healing, often leading to scar formation. Hence, the development of innovative biomaterials for wound healing is essential. Natural and synthetic polymers are used extensively for wound dressings and scaffold production. Both natural and synthetic polymers have beneficial properties and limitations, so they are often used in combination to overcome overcome their individual limitations. The use of different polymers in the production of biomaterials has proven to be a promising alternative for the treatment of wounds, as their capacity to accelerate the healing process has been demonstrated in many studies. Thus, this work focuses on describing several currently commercially available solutions used for the management of skin wounds, such as polymeric biomaterials for skin substitutes. New directions, strategies, and innovative technologies for the design of polymeric biomaterials are also addressed, providing solutions for deep burns, personalized care and faster healing.
皮肤反映了一个人的健康状况,其重要性足以影响一个人的情绪和心理行为。在这种情况下,伤口的有效治疗是一个主要关注点,因为几种传统的伤口愈合材料未能实现充分愈合,常常导致疤痕形成。因此,开发用于伤口愈合的创新生物材料至关重要。天然和合成聚合物被广泛用于伤口敷料和支架生产。天然和合成聚合物都有其有益特性和局限性,因此它们常常被组合使用以克服各自的局限性。在生物材料生产中使用不同的聚合物已被证明是治疗伤口的一种有前景的替代方法,因为许多研究已经证明了它们加速愈合过程的能力。因此,这项工作着重描述几种目前用于皮肤伤口管理的市售解决方案,例如用于皮肤替代物的聚合物生物材料。还探讨了聚合物生物材料设计的新方向、策略和创新技术,为深度烧伤、个性化护理和更快愈合提供解决方案。