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微量元素镁:高血压管理的关键因素。

Trace element magnesium: a key player in hypertension management.

机构信息

Department of Biotechnology, School of Life Sciences, Central University of Tamil Nadu, Neelakudi, Thiruvarur, 610005, Tamil Nadu, India.

出版信息

Hypertens Res. 2023 Oct;46(10):2442-2444. doi: 10.1038/s41440-023-01404-w. Epub 2023 Aug 15.

DOI:10.1038/s41440-023-01404-w
PMID:37582848
Abstract

Magnesium deficit decreases nitric oxide production and oxidative stress, but calcium efflux in VSMC enhances proliferation, migration, and remodelling. These pathways contribute to cardiovascular disorders, hypertension, insulin resistance, sodium retention, fluid retention, and blood volume. Magnesium supplements could be beneficial.

摘要

镁缺乏会减少一氧化氮的产生和氧化应激,但血管平滑肌细胞中的钙外流会增强增殖、迁移和重塑。这些途径会导致心血管疾病、高血压、胰岛素抵抗、钠潴留、液体潴留和血容量增加。补充镁可能会有帮助。

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Trace element magnesium: a key player in hypertension management.微量元素镁:高血压管理的关键因素。
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Role of dietary magnesium in cardiovascular disease prevention, insulin sensitivity and diabetes.膳食镁在心血管疾病预防、胰岛素敏感性及糖尿病中的作用。
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Influence of mineral and vitamin supplements on pregnancy outcome.矿物质和维生素补充剂对妊娠结局的影响。
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Magnesium, calcium and trace elements in spontaneously hypertensive rats.
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Hypomagnesemia: exploring its multifaceted health impacts and associations with blood pressure regulation and metabolic syndrome.低镁血症:探讨其多方面的健康影响以及与血压调节和代谢综合征的关联。
Diabetol Metab Syndr. 2025 Jun 16;17(1):217. doi: 10.1186/s13098-025-01772-y.
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Relation between serum magnesium and outcome in patients with Escherichia coli sepsis.血清镁与大肠杆菌败血症患者预后的关系。
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本文引用的文献

1
Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.补充镁对改善2型糖尿病患者高血糖、高胆固醇血症和高血压的影响:24项随机对照试验的汇总分析
Front Nutr. 2023 Jan 18;9:1020327. doi: 10.3389/fnut.2022.1020327. eCollection 2022.
2
Effectively Prescribing Oral Magnesium Therapy for Hypertension: A Categorized Systematic Review of 49 Clinical Trials.有效开具口服镁治疗高血压处方:49 项临床试验的分类系统评价。
Nutrients. 2021 Jan 10;13(1):195. doi: 10.3390/nu13010195.
3
Magnesium and Hypertension in Old Age.
镁与老年高血压。
Nutrients. 2020 Dec 31;13(1):139. doi: 10.3390/nu13010139.
4
Magnesium Supplementation Attenuates Pulmonary Hypertension via Regulation of Magnesium Transporters.镁补充通过调节镁转运体减轻肺动脉高压。
Hypertension. 2021 Feb;77(2):617-631. doi: 10.1161/HYPERTENSIONAHA.120.14909. Epub 2020 Dec 28.
5
Magnesium: The Forgotten Electrolyte-A Review on Hypomagnesemia.镁:被遗忘的电解质——低镁血症综述
Med Sci (Basel). 2019 Apr 4;7(4):56. doi: 10.3390/medsci7040056.
6
Mechanisms of the effect of magnesium salts in preeclampsia.镁盐在子痫前期中的作用机制。
Placenta. 2018 Sep;69:134-139. doi: 10.1016/j.placenta.2018.04.011. Epub 2018 Apr 24.
7
Dietary Magnesium and Cardiovascular Disease: A Review with Emphasis in Epidemiological Studies.膳食镁与心血管疾病:以流行病学研究为重点的综述。
Nutrients. 2018 Feb 1;10(2):168. doi: 10.3390/nu10020168.
8
The role of magnesium in hypertension and cardiovascular disease.镁在高血压和心血管疾病中的作用。
J Clin Hypertens (Greenwich). 2011 Nov;13(11):843-7. doi: 10.1111/j.1751-7176.2011.00538.x. Epub 2011 Sep 26.
9
Magnesium supplements may enhance the effect of antihypertensive medications in stage 1 hypertensive subjects.镁补充剂可能增强 1 期高血压患者抗高血压药物的疗效。
Magnes Res. 2010 Mar;23(1):27-40. doi: 10.1684/mrh.2010.0198. Epub 2010 Mar 12.
10
Oral magnesium therapy improves endothelial function in patients with coronary artery disease.口服镁剂治疗可改善冠心病患者的内皮功能。
Circulation. 2000 Nov 7;102(19):2353-8. doi: 10.1161/01.cir.102.19.2353.