Kumar Jitesh, Patel Tirath, Sugandh Fnu, Dev Jyotishna, Kumar Umesh, Adeeb Maham, Kachhadia Meet Popatbhai, Puri Piyush, Prachi Fnu, Zaman Mohammad Uzair, Kumar Satesh, Varrassi Giustino, Syed Abdul Rehman Shah
Internal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Medical Student, American University of Antigua, St. John's, ATG.
Cureus. 2023 Jul 15;15(7):e41914. doi: 10.7759/cureus.41914. eCollection 2023 Jul.
Brain rehabilitation and recovery for people with neurological disorders, such as stroke, traumatic brain injury (TBI), and neurodegenerative diseases, depend mainly on neuroplasticity, the brain's capacity to restructure and adapt. This literature review aims to look into cutting-edge methods and treatments that support neuroplasticity and recovery in these groups. A thorough search of electronic databases revealed a wide range of research and papers investigating several neuroplasticity-targeting methods, such as cognitive training, physical activity, non-invasive brain stimulation, and pharmaceutical interventions. The results indicate that these therapies can control neuroplasticity and improve motor, mental, and sensory function. In addition, cutting-edge approaches, such as virtual reality (VR) and brain-computer interfaces (BCIs), promise to increase neuroplasticity and foster rehabilitation. However, many issues and restrictions still need to be resolved, including the demand for individualized treatments and the absence of defined standards. In conclusion, this review emphasizes the significance of neuroplasticity in brain rehabilitation. It identifies novel strategies and treatments that promise to enhance recovery in patients with neurological illnesses. Future studies should concentrate on improving these therapies and developing evidence-based standards to direct clinical practice and enhance outcomes for this vulnerable population.
对于患有神经系统疾病（如中风、创伤性脑损伤（TBI）和神经退行性疾病）的人来说，大脑康复和恢复主要依赖于神经可塑性，即大脑进行结构重组和适应的能力。这篇文献综述旨在探究支持这些人群神经可塑性和恢复的前沿方法与治疗手段。对电子数据库进行全面检索后发现了大量研究及论文，它们探讨了多种针对神经可塑性的方法，如认知训练、体育活动、非侵入性脑刺激和药物干预。结果表明，这些疗法能够调控神经可塑性，并改善运动、心理和感觉功能。此外，虚拟现实（VR）和脑机接口（BCI）等前沿方法有望增强神经可塑性并促进康复。然而，仍有许多问题和限制有待解决，包括对个性化治疗的需求以及缺乏明确的标准。总之，本综述强调了神经可塑性在大脑康复中的重要性。它确定了有望提高神经疾病患者恢复效果的新策略和治疗方法。未来的研究应专注于改进这些疗法，并制定基于证据的标准，以指导临床实践并改善这一弱势群体的治疗效果。
