Garg Gaurav, Patidar Narendra, Dubey Satyendra
Department of Oculoplasty, Oncology and Aesthetics, View Care, Delhi, India.
Department of Orbit and Oculoplasty, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India.
Oman J Ophthalmol. 2023 Jun 27;16(2):359-362. doi: 10.4103/ojo.ojo_343_21. eCollection 2023 May-Aug.
Chronic myeloid leukemia (CML) rarely presents under 15 years of age, and its incidence is as low as 2% of all leukemia. Ophthalmic manifestations often present either initially with the diagnosis or as a sign of relapse after remission. The recommended treatment is systemic chemotherapy, intrathecal chemotherapy, ocular irradiation, and/or intravitreal methotrexate. Herein, we report a 13-year-old child with a history of CML and central nervous system relapse under remission currently. He presented to us with bilateral ophthalmic relapse. He was treated with ocular irradiation and intrathecal chemotherapy. On follow-up, the ophthalmic infiltration showed resolution, which was also seen on multimodal imaging.
慢性髓性白血病（CML）在15岁以下儿童中很少见，其发病率仅占所有白血病的2%。眼部表现通常在疾病初诊时出现，或作为缓解后复发的体征。推荐的治疗方法包括全身化疗、鞘内化疗、眼部放疗和/或玻璃体内注射甲氨蝶呤。在此，我们报告一名13岁儿童，有慢性髓性白血病病史，目前处于缓解期但出现中枢神经系统复发。他因双侧眼部复发前来就诊。给予其眼部放疗和鞘内化疗。随访时，眼部浸润表现消退，多模态影像学检查也证实了这一点。
