Central Laboratory, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China.
Central Laboratory, Ningxia Medical University Affiliated People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China.
BMJ Open. 2023 Aug 22;13(8):e068655. doi: 10.1136/bmjopen-2022-068655.
To evaluate the changing trends of hospitalisation for patients with liver cirrhosis between 2015 and 2019 by using hospitalisation summary records in Ningxia Hui Autonomous Region (NHAR), China.
A cross-sectional study.
Hospitalisation summary records between 1 January 2015 and 31 December 2019 from 28 top-ranking hospitals in NHAR were extracted and rigorously analysed.
During the study period, hospitalisation records referring to liver cirrhosis were included. Records with missing data were excluded. A total of 16 566 patients with liver cirrhosis were included in this study.
International Classification of Diseases codes, tenth version (ICD-10) and text-diagnoses were used to identify hospitalisation records referring to liver cirrhosis.
Between 2015 and 2019, hospitalisation rates for liver cirrhosis declined from 8.38% to 5.57%. Chronic viral hepatitis accounted for almost 70% of all liver cirrhosis admissions; the remaining 30% of patients were admitted due to non-viral hepatitis cirrhosis (28.06%) and alcoholic cirrhosis (2.05%). The male-to-female hospitalisation rate ratio for liver cirrhosis was 2.57. The hospitalisation rate for workers with hepatitis cirrhosis was significantly higher than farmers (hospitalisation rate ratio (RR)=1.06, 95% CI 1.01 to 1.15, p<0.001); this was also the case for alcoholic cirrhosis (RR=5.23, 95% CI 3.34 to 8.20). However, the hospitalisation rate for workers with non-viral hepatitis cirrhosis was significantly lower than for farmers (RR=5.23, 95% CI 3.34 to 8.20, p<0.001). The hospitalisation rate increased in patients over the age of 30 years and reached a peak at the age of 45-50 years.
The hospitalisation rate for liver cirrhosis has declined over recent years and chronic viral hepatitis remains the major cause of liver cirrhosis in NHAR. Hospitalisation summary records can efficiently reflect the local changing trends of hospitalisation for liver cirrhosis and represent an efficient strategy for the surveillance of chronic disease.
利用中国宁夏回族自治区（NHAR）住院总结记录评估 2015 年至 2019 年期间肝硬化患者住院的变化趋势。
横断面研究。
从 NHAR 28 家顶级医院提取并严格分析 2015 年 1 月 1 日至 2019 年 12 月 31 日期间的住院总结记录。
在研究期间，包括肝硬化住院记录。排除数据缺失的记录。共有 16566 名肝硬化患者纳入本研究。
国际疾病分类第十版（ICD-10）和文本诊断用于识别肝硬化住院记录。
2015 年至 2019 年期间，肝硬化住院率从 8.38%下降至 5.57%。慢性病毒性肝炎占所有肝硬化入院的近 70%；其余 30%的患者因非病毒性肝炎肝硬化（28.06%）和酒精性肝硬化（2.05%）入院。肝硬化的男女住院率比为 2.57。乙型肝炎肝硬化患者的住院率明显高于农民（住院率比（RR）=1.06，95%置信区间 1.01 至 1.15，p<0.001）；酒精性肝硬化也是如此（RR=5.23，95%置信区间 3.34 至 8.20）。然而，非病毒性肝炎肝硬化患者的住院率明显低于农民（RR=5.23，95%置信区间 3.34 至 8.20，p<0.001）。住院率在 30 岁以上的患者中增加，并在 45-50 岁达到峰值。
近年来，肝硬化的住院率有所下降，慢性病毒性肝炎仍然是 NHAR 肝硬化的主要原因。住院总结记录可以有效地反映当地肝硬化住院变化趋势，是慢性病监测的有效策略。
