Gomez-Blanco Nina, Prato Maurizio
Carbon Bionanotechnology Group, Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), 20014, San Sebastián, Spain.
Department of Chemical and Pharmaceutical Sciences, INSTM - University of Trieste, Via L. Giorgieri 1, 34127, Trieste, Italy.
Commun Chem. 2023 Aug 23;6(1):174. doi: 10.1038/s42004-023-00983-6.
Using metal coordination to assemble carbon nanodots (CND) into clusters can enhance their photophysical properties for applications in sensing and biomedicine. Water-soluble clusters of CNDs are prepared by one-step microwave synthesis starting from ethylenediaminetetraacetic acid, ethylenediamine and MnCl·4HO as precursors. Transmission electron microscopy and powder X-Ray diffraction techniques indicate that the resulting clusters form spherical particles of 150 nm constituted by amorphous CNDs joined together with Mn ions in a laminar crystalline structure. The nanomaterial assemblies show remarkable fluorescence quantum yields (0.17-0.20) and magnetic resonance imaging capability (r = 2.3-3.8 mM.s). In addition, they can be stabilized in aqueous solutions by phosphate ligands, providing a promising dual imaging platform for use in biological systems.
利用金属配位作用将碳纳米点（CND）组装成簇可增强其光物理性质，以用于传感和生物医学应用。以乙二胺四乙酸、乙二胺和MnCl·4HO为前体，通过一步微波合成法制备了水溶性的CND簇。透射电子显微镜和粉末X射线衍射技术表明，所得的簇形成了由非晶态CND与Mn离子以层状晶体结构连接在一起构成的150 nm球形颗粒。这种纳米材料组装体表现出显著的荧光量子产率（0.17 - 0.20）和磁共振成像能力（r = 2.3 - 3.8 mM.s）。此外，它们可以通过磷酸盐配体在水溶液中稳定，为生物系统提供了一个有前景的双成像平台。
