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Editorial: 3D organoid and organ-on-a-chip and their applications for virology and antiviral research.

作者信息

Yin Yuebang, Xu Lei, Steinway Steven Nathaniel

机构信息

Department of Gastroenterology and Hepatology, Erasmus University Medical Center, CE Rotterdam, Rotterdam, Netherlands.

National Key Laboratory of Crop Improvement for Stress Tolerance and Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Xianyang, Shaanxi, China.

出版信息

Front Microbiol. 2023 Aug 8;14:1266136. doi: 10.3389/fmicb.2023.1266136. eCollection 2023.

DOI:10.3389/fmicb.2023.1266136
PMID:37614596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10443217/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f9b/10443217/50284e98656b/fmicb-14-1266136-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f9b/10443217/50284e98656b/fmicb-14-1266136-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f9b/10443217/50284e98656b/fmicb-14-1266136-g0001.jpg

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A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.用于快速鉴定候选抗病毒治疗药物和预防药物的人呼吸道芯片。
Nat Biomed Eng. 2021 Aug;5(8):815-829. doi: 10.1038/s41551-021-00718-9. Epub 2021 May 3.
2
Single-Cell Sequencing and Organoids: A Powerful Combination for Modelling Organ Development and Diseases.单细胞测序和类器官：模拟器官发育和疾病的强大组合。
Rev Physiol Biochem Pharmacol. 2021;179:189-210. doi: 10.1007/112_2020_47.
3
Organ-on-a-Chip: A New Paradigm for Drug Development.
器官芯片：药物开发的新模式。
Trends Pharmacol Sci. 2021 Feb;42(2):119-133. doi: 10.1016/j.tips.2020.11.009. Epub 2020 Dec 16.
4
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.使用肺和结肠类器官鉴定 SARS-CoV-2 抑制剂。
Nature. 2021 Jan;589(7841):270-275. doi: 10.1038/s41586-020-2901-9. Epub 2020 Oct 28.
5
Mini-gut: a promising model for drug development.迷你肠道：药物研发的有前景模型。
Drug Discov Today. 2019 Sep;24(9):1784-1794. doi: 10.1016/j.drudis.2019.06.006. Epub 2019 Jun 15.
6
Enteroids for Nutritional Studies.肠类器官用于营养研究。
Mol Nutr Food Res. 2019 Aug;63(16):e1801143. doi: 10.1002/mnfr.201801143. Epub 2019 Apr 10.
7
Multi-omic measurements of heterogeneity in HeLa cells across laboratories.多组学测量 HeLa 细胞在不同实验室间的异质性。
Nat Biotechnol. 2019 Mar;37(3):314-322. doi: 10.1038/s41587-019-0037-y. Epub 2019 Feb 18.
8
Organ/body-on-a-chip based on microfluidic technology for drug discovery.基于微流控技术的用于药物发现的器官/芯片上的人体模型
Drug Metab Pharmacokinet. 2018 Feb;33(1):43-48. doi: 10.1016/j.dmpk.2017.11.003. Epub 2017 Nov 13.
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Modeling rotavirus infection and antiviral therapy using primary intestinal organoids.利用原代肠类器官建立轮状病毒感染和抗病毒治疗模型。
Antiviral Res. 2015 Nov;123:120-31. doi: 10.1016/j.antiviral.2015.09.010. Epub 2015 Sep 25.
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Genomic instability of osteosarcoma cell lines in culture: impact on the prediction of metastasis relevant genes.培养的骨肉瘤细胞系的基因组不稳定性：对转移相关基因预测的影响
PLoS One. 2015 May 19;10(5):e0125611. doi: 10.1371/journal.pone.0125611. eCollection 2015.