Gandla Kumaraswamy, Kumar K Praveen, Rajasulochana P, Charde Manoj Shrawan, Rana Ritesh, Singh Laliteshwar Pratap, Haque M Akiful, Bakshi Vasudha, Siddiqui Falak A, Khan Sharuk L, Ganguly S
Department of Pharmaceutical Analysis, Chaitanya (Deemed to be University), Hyderabad 500075, India.
Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Government of NCT of Delhi, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi 110017, India.
Gels. 2023 Aug 18;9(8):669. doi: 10.3390/gels9080669.
Nanocomposite polymeric gels infused with fluorescent nanoparticles have surfaced as a propitious category of substances for biomedical purposes owing to their exceptional characteristics. The aforementioned materials possess a blend of desirable characteristics, including biocompatibility, biodegradability, drug encapsulation, controlled release capabilities, and optical properties that are conducive to imaging and tracking. This paper presents a comprehensive analysis of the synthesis and characterization of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels, as well as their biomedical applications, such as drug delivery, imaging, and tissue engineering. In this discourse, we deliberate upon the merits and obstacles linked to these substances, encompassing biocompatibility, drug encapsulation, optical characteristics, and scalability. The present study aims to provide an overall evaluation of the potential of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels for biomedical applications. Additionally, emerging trends and future directions for research in this area are highlighted.
注入荧光纳米颗粒的纳米复合聚合物凝胶因其卓越特性已成为一类用于生物医学目的的有前景的物质。上述材料具备一系列理想特性，包括生物相容性、生物可降解性、药物封装、控释能力以及有利于成像和追踪的光学特性。本文全面分析了注入荧光纳米颗粒的纳米复合聚合物凝胶的合成与表征，以及它们在生物医学领域的应用，如药物递送、成像和组织工程。在本文中，我们探讨了与这些物质相关的优点和障碍，包括生物相容性、药物封装、光学特性和可扩展性。本研究旨在全面评估注入荧光纳米颗粒的纳米复合聚合物凝胶在生物医学应用中的潜力。此外，还强调了该领域研究的新兴趋势和未来方向。
