Hetta Helal F, Ramadan Yasmin N, Al-Kadmy Israa M S, Ellah Noura H Abd, Shbibe Lama, Battah Basem
Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.
Department of Microbiology and Immunology, Faculty of Pharmacy, Assiut University, Assiut 71515, Egypt.
Pathogens. 2023 Aug 13;12(8):1033. doi: 10.3390/pathogens12081033.
An emerging multidrug-resistant pathogenic yeast called has a high potential to spread quickly among hospitalized patients and immunodeficient patients causing nosocomial outbreaks. It has the potential to cause pandemic outbreaks in about 45 nations with high mortality rates. Additionally, the fungus has become resistant to decontamination techniques and can survive for weeks in a hospital environment. Nanoparticles might be a good substitute to treat illnesses brought on by this newly discovered pathogen. Nanoparticles have become a trend and hot topic in recent years to combat this fatal fungus. This review gives a general insight into the epidemiology of and infection. It discusses the current conventional therapy and mechanism of resistance development. Furthermore, it focuses on nanoparticles, their different types, and up-to-date trials to evaluate the promising efficacy of nanoparticles with respect to .
一种新出现的多重耐药致病酵母具有在住院患者和免疫缺陷患者中迅速传播并引发医院感染暴发的高度可能性。它有可能在约45个死亡率高的国家引发大流行疫情。此外，这种真菌已对去污技术产生耐药性，并且能在医院环境中存活数周。纳米颗粒可能是治疗由这种新发现病原体引起疾病的良好替代品。近年来，纳米颗粒已成为对抗这种致命真菌的一种趋势和热门话题。本综述对该酵母的流行病学和感染情况进行了总体概述。它讨论了当前的传统疗法及耐药性产生机制。此外，它聚焦于纳米颗粒、其不同类型以及最新的试验，以评估纳米颗粒针对该酵母的潜在疗效。
