Maggi Raffaella, De Paolis Livia, De Santis Daria, Vellone Valerio Gaetano, De Ciucis Chiara Grazia, Fruscione Floriana, Mazzocco Katia, Ghelardi Alessandro, Marruchella Giuseppe, Razzuoli Elisabetta
Veterinary Practitioner, Via Cassia 829, 00189 Rome, Italy.
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, National Reference Center of Veterinary and Comparative Oncology (CEROVEC), Piazza Borgo Pila 29/34, 16129 Genova, Italy.
Pathogens. 2023 Aug 18;12(8):1059. doi: 10.3390/pathogens12081059.
Papillomas are benign epithelial lesions protruding on the epithelial surfaces as finger-like or warty projections. These lesions are often caused by papillomavirus (PV) infection. Congenital papillomas have been reported in foals. However, to date, no evidence of PV infection has been provided. In the present paper, we describe the main clinical-pathological features of a congenital papilloma observed in a foal. In addition, biomolecular tests demonstrated BPV1 infection in the case under study. Such data stimulate further investigations, even on archived samples, aiming to clarifying the etiology of equine congenital papilloma and the clinical relevance, if any, of BPV1 vertical transmission in horses.
乳头状瘤是突出于上皮表面的良性上皮性病变，呈指状或疣状突起。这些病变通常由乳头瘤病毒（PV）感染引起。有报道称马驹存在先天性乳头状瘤。然而，迄今为止，尚未提供PV感染的证据。在本文中，我们描述了一匹马驹身上观察到的先天性乳头状瘤的主要临床病理特征。此外，生物分子检测表明所研究病例存在牛乳头瘤病毒1型（BPV1）感染。这些数据促使人们开展进一步研究，甚至对存档样本进行研究，旨在阐明马先天性乳头状瘤的病因以及BPV1在马体内垂直传播的临床相关性（若有的话）。
