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机器人前列腺切除术新成像技术的系统评价:从分子成像到增强现实

A Systematic Review of New Imaging Technologies for Robotic Prostatectomy: From Molecular Imaging to Augmented Reality.

作者信息

Rodler Severin, Kidess Marc Anwar, Westhofen Thilo, Kowalewski Karl-Friedrich, Belenchon Ines Rivero, Taratkin Mark, Puliatti Stefano, Gómez Rivas Juan, Veccia Alessandro, Piazza Pietro, Checcucci Enrico, Stief Christian Georg, Cacciamani Giovanni Enrico

机构信息

Department of Urology, University Hospital of Munich, 81377 Munich, Germany.

Department of Urology, Klinikum Mannheim, 68167 Mannheim, Germany.

出版信息

J Clin Med. 2023 Aug 21;12(16):5425. doi: 10.3390/jcm12165425.

DOI:10.3390/jcm12165425
PMID:37629467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10455161/
Abstract

New imaging technologies play a pivotal role in the current management of patients with prostate cancer. Robotic assisted radical prostatectomy (RARP) is a standard of care for localized disease and through the already imaging-based console subject of research towards combinations of imaging technologies and RARP as well as their impact on surgical outcomes. Therefore, we aimed to provide a comprehensive analysis of the currently available literature for new imaging technologies for RARP. On 24 January 2023, we performed a systematic review of the current literature on Pubmed, Scopus and Web of Science according to the PRISMA guidelines and Oxford levels of evidence. A total of 46 studies were identified of which 19 studies focus on imaging of the primary tumor, 12 studies on the intraoperative tumor detection of lymph nodes and 15 studies on the training of surgeons. While the feasibility of combined approaches using new imaging technologies including MRI, PSMA-PET CT or intraoperatively applied radioactive and fluorescent dyes has been demonstrated, the prospective confirmation of improvements in surgical outcomes is currently ongoing.

摘要

新的成像技术在当前前列腺癌患者的管理中起着关键作用。机器人辅助根治性前列腺切除术(RARP)是局限性疾病的标准治疗方法,并且基于成像的控制台已经成为研究成像技术与RARP的组合及其对手术结果影响的主题。因此,我们旨在对目前可获得的关于RARP新成像技术的文献进行全面分析。2023年1月24日,我们根据PRISMA指南和牛津证据等级对PubMed、Scopus和科学网的当前文献进行了系统综述。共确定了46项研究,其中19项研究聚焦于原发性肿瘤的成像,12项研究关注术中淋巴结肿瘤检测,15项研究涉及外科医生的培训。虽然包括MRI、PSMA-PET CT或术中应用放射性和荧光染料在内的新成像技术联合应用方法的可行性已得到证实,但目前正在对手术结果的改善进行前瞻性确认。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09df/10455161/83bf8f6de17c/jcm-12-05425-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09df/10455161/103fe33bdb77/jcm-12-05425-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09df/10455161/83bf8f6de17c/jcm-12-05425-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09df/10455161/103fe33bdb77/jcm-12-05425-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09df/10455161/83bf8f6de17c/jcm-12-05425-g002.jpg

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本文引用的文献

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Nat Med. 2023 Jan;29(1):14-15. doi: 10.1038/s41591-022-02139-w.
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Fluorescence-guided extended pelvic lymphadenectomy during robotic radical prostatectomy.
更正:我们能否依靠磁共振成像进行前列腺癌检测和手术规划?对大量接受经会阴定位活检的患者进行的综合分析。
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