[通过分子杂交法检测乙肝表面抗原携带者及贫血患者体内的乙肝病毒DNA]
[Detection of the DNA of the hepatitis B virus by molecular hybridization in HBsAg carriers and anemia patients].
作者信息
Granovskiĭ N N, Vlasikhina E M, Dotsenko G N, Uspenskiĭ M V, Zhdanov V M
出版信息
Vopr Virusol. 1986 Jul-Aug;31(4):449-52.
PMID:3765569
Abstract
The method of molecular hybridization using cloned DNA of hepatitis B virus as a probe demonstrated the presence of virus-specific DNAs in sera of former blood donors, HBsAg carriers. Among HBsAg-positive patients with anemias, hepatitis B virus DNA was detected in half of the examined subjects which in all cases was accompanied by the presence of HBeAg in their blood.
摘要
以乙肝病毒克隆DNA为探针的分子杂交方法表明，在曾是献血者的乙肝表面抗原（HBsAg）携带者的血清中存在病毒特异性DNA。在患有贫血的HBsAg阳性患者中，一半受检者检测到乙肝病毒DNA，所有这些病例中其血液中均伴有e抗原（HBeAg）。
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