伊朗西南部系统性红斑狼疮患者的健康相关生活质量及其相关因素：一项横断面研究。
Health-related quality of life and its related factors in patients with systemic lupus erythematosus in southwest Iran: a cross-sectional study.
机构信息
Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Occupational Therapy, Zanjan University of Medical Sciences, Zanjan, Iran.
出版信息
BMC Psychol. 2023 Sep 1;11(1):259. doi: 10.1186/s40359-023-01300-5.
BACKGROUND
Quality of life (QoL) is an important measure in health assessment. It is impacted by unclear factors in Systemic Lupus Erythematosus (SLE) patients. The study aimed to investigate the factors related to QoL in SLE patients.
METHODS
This cross-sectional study was performed on 140 (136 women and four men) Iranian SLE patients of Hafiz Hospital from June 2019 to August 2020. The Lupus Erythematosus Quality of Life Questionnaire (LEQoL) was used to evaluate the quality of life. The patients were evaluated with this questionnaire for four weeks in eight dimensions health, emotional health, body image, pain, planning, intimate relationships, and the burden of others. Related factors of LEQoL were evaluated using multivariable linear regression.
RESULTS
The mean age was 34.09(8.96) years. The total mean QoL Score was 65.5 ± 22.4. The multivariable analysis showed that duration of disease (β:-1.12, 95% CI:-1.44 to -0.79, P:0.001), physical activity(β:-12.99, 95% CI:-19.2 to -6.13, P:0.001), kidney involvement (β:-9.2, 95% CI:-16.61 to -2.79, P:0.03) and skin involvement(β:-8.7, 95% CI:-17.2 to -0.2, P:0.031) were significantly related to the total mean QOL score of SLE patients.
CONCLUSION
The QoL of Iranian patients with SLE was low. Age and gender can be related to the decrease in the QoL of patients with SLE. Increasing the disease duration, physical activity, kidney involvement, and skin involvement can be related to the decrease in the QOL of Iranian patients with SLE.
背景
生活质量（QoL）是健康评估的重要指标。它受到系统性红斑狼疮（SLE）患者中不明因素的影响。本研究旨在探讨 SLE 患者生活质量相关的因素。
方法
本横断面研究于 2019 年 6 月至 2020 年 8 月在哈菲兹医院对 140 名（136 名女性和 4 名男性）伊朗 SLE 患者进行。使用红斑狼疮生活质量问卷（LEQoL）评估生活质量。患者在四周内通过该问卷评估 8 个维度的健康、情绪健康、身体形象、疼痛、计划、亲密关系和他人负担。使用多变量线性回归评估 LEQoL 的相关因素。
结果
平均年龄为 34.09（8.96）岁。总平均 QoL 评分 65.5±22.4。多变量分析显示，疾病持续时间（β：-1.12，95%CI：-1.44 至-0.79，P：0.001）、体力活动（β：-12.99，95%CI：-19.2 至-6.13，P：0.001）、肾脏受累（β：-9.2，95%CI：-16.61 至-2.79，P：0.03）和皮肤受累（β：-8.7，95%CI：-17.2 至-0.2，P：0.031）与 SLE 患者总平均 QOL 评分显著相关。
结论
伊朗 SLE 患者的生活质量较低。年龄和性别可能与 SLE 患者生活质量下降有关。增加疾病持续时间、体力活动、肾脏受累和皮肤受累可能与伊朗 SLE 患者生活质量下降有关。
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