Huq A, Huq S A, Grimes D J, O'Brien M, Chu K H, Capuzzo J M, Colwell R R
Appl Environ Microbiol. 1986 Sep;52(3):586-8. doi: 10.1128/aem.52.3.586-588.1986.
Attachment of Vibrio cholerae to the mucosal surface of the intestine is considered to be an important virulence characteristic. Vibrio cholerae, an autochthonous member of brackish water and estuarine bacterial communities, also attaches to crustacea, a significant factor in multiplication and survival of V. cholerae in nature. The ability of V. cholerae to attach to the gut wall of the blue crab (Callinectes sapidus) was examined, and attachment was observed only in the hindgut and not the midgut of crabs, confirming a requirement for chitin in the attachment of V. cholerae to invertebrate and zooplankton surfaces. The new finding of attachment of V. cholerae to the hindgut of crabs may be correlated with the epidemiology and transmission of cholera in the aquatic environment. The crab model may also prove useful in elucidating the mechanism(s) of ion transport in crustacea.
霍乱弧菌附着于肠道黏膜表面被认为是一项重要的毒力特征。霍乱弧菌是咸淡水和河口细菌群落的本地成员，它也能附着于甲壳类动物，这是霍乱弧菌在自然界繁殖和生存的一个重要因素。研究了霍乱弧菌附着于蓝蟹（Callinectes sapidus）肠壁的能力，结果发现仅在后肠有附着现象，中肠未出现，这证实霍乱弧菌附着于无脊椎动物和浮游动物表面需要几丁质。霍乱弧菌附着于蟹后肠这一新发现可能与霍乱在水生环境中的流行病学及传播相关。蟹模型或许在阐明甲壳类动物离子转运机制方面也会被证明是有用的。
