Asherson R A, Benbow A G, Speirs C J, Jackson N, Hughes G R
Ann Rheum Dis. 1986 Sep;45(9):771-3. doi: 10.1136/ard.45.9.771.
A patient who developed pulmonary hypertension and systemic lupus erythematosus as a complication of hydralazine therapy is reported. She was a slow acetylator and in addition was found to have a null allele at the C4A locus.
报告了一名因肼屈嗪治疗出现肺动脉高压和系统性红斑狼疮并发症的患者。她是慢乙酰化者,此外还发现其C4A基因座存在无效等位基因。