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1990 年至 2019 年中国归因于环境颗粒物污染的全因和特定原因死亡率趋势:二次数据分析研究。

Trends in all causes and cause specific mortality attributable to ambient particulate matter pollution in China from 1990 to 2019: A secondary data analysis study.

机构信息

Department of Health Management & Institute of Health Management, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China.

出版信息

PLoS One. 2023 Sep 8;18(9):e0291262. doi: 10.1371/journal.pone.0291262. eCollection 2023.

Abstract

BACKGROUND

Particularly fine particulate matter (PM2.5) has become a significant public health concern in China due to its harmful effects on human health. This study aimed to examine the trends in all causes and cause specific morality burden attributable to PM2.5 pollution in China.

METHODS

We extracted data on all causes and cause specific mortality data attributable to PM2.5 exposure for the period 1990-2019 in China from the Global Burden of Disease 2019. The average annual percent change (AAPC) in age-standardized mortality rates (ASMR) and years of life lost (YLLs) due to PM2.5 exposure were calculated using the Joinpoint Regression Program. Using Pearson's correlation, we estimated association between burden trends, urban green space area, and higher education proportions.

RESULTS

During the period 1990-1999, there were increases in mortality rates for All causes (1.6%, 95% CI: 1.5% to 1.8%), Diabetes mellitus (5.2%, 95% CI: 4.9% to 5.5%), Encephalitis (3.1%, 95% CI: 2.6% to 3.5%), Ischemic heart disease (3.3%, 95% CI: 3% to 3.6%), and Tracheal, bronchus and lung cancer (5%, 95% CI: 4.7% to 5.2%). In the period 2010-2019, Diabetes mellitus still showed an increase in mortality rates, but at a lower rate with an AAPC of 1.2% (95% CI: 1% to 1.4%). Tracheal bronchus and lung cancer showed a smaller increase in this period, with an AAPC of 0.5% (95% CI: 0.3% to 0.6%). In terms of YLLs, the trends appear to be similar.

CONCLUSION

Our findings highlight increasing trends in disease burden attributable to PM2.5 in China, particularly for diabetes mellitus, tracheal, bronchus, and lung cancer.

摘要

背景

由于细颗粒物(PM2.5)对人类健康的有害影响,其已成为中国一个重要的公共卫生关注点。本研究旨在研究中国 PM2.5 污染所致全死因和死因特异性死亡负担的变化趋势。

方法

我们从 2019 年全球疾病负担研究中提取了 1990 年至 2019 年中国 PM2.5 暴露所致全死因和死因特异性死亡数据。使用 Joinpoint 回归程序计算了归因于 PM2.5 暴露的年龄标准化死亡率(ASMR)和生命损失年(YLL)的平均年变化百分比(AAPC)。使用 Pearson 相关系数,我们评估了负担变化趋势与城市绿地面积和高等教育比例之间的相关性。

结果

在 1990 年至 1999 年期间,全死因(1.6%,95%CI:1.5%至 1.8%)、糖尿病(5.2%,95%CI:4.9%至 5.5%)、脑炎(3.1%,95%CI:2.6%至 3.5%)、缺血性心脏病(3.3%,95%CI:3%至 3.6%)和气管、支气管和肺癌(5%,95%CI:4.7%至 5.2%)的死亡率有所增加。在 2010 年至 2019 年期间,糖尿病的死亡率仍呈上升趋势,但上升速度较慢,AAPC 为 1.2%(95%CI:1%至 1.4%)。在此期间,气管、支气管和肺癌的死亡率增长较小,AAPC 为 0.5%(95%CI:0.3%至 0.6%)。就 YLL 而言,趋势似乎相似。

结论

我们的研究结果突出了中国 PM2.5 所致疾病负担的增长趋势,尤其是糖尿病、气管、支气管和肺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9811/10490985/b9005b9ee45b/pone.0291262.g001.jpg

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