巨噬细胞向肿瘤相关巨噬细胞的致瘤性重编程：转录、表观遗传和代谢基础
Corruptive Reprograming of Macrophages into Tumor-Associated Macrophages: The Transcriptional, Epigenetic and Metabolic Basis.
作者信息
Ahmad Aamir
机构信息
Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha 3050, Qatar.
Dermatology Institute, Academic Health System, Hamad Medical Corporation, Doha 3050, Qatar.
出版信息
Cancers (Basel). 2023 Aug 28;15(17):4291. doi: 10.3390/cancers15174291.
Abstract
The tumor microenvironment (TME) is an important place with regard to the growth and sustenance of tumor cells [...].
摘要
肿瘤微环境（TME）是与肿瘤细胞的生长和维持相关的重要场所[...]。
相似文献
1
Corruptive Reprograming of Macrophages into Tumor-Associated Macrophages: The Transcriptional, Epigenetic and Metabolic Basis.巨噬细胞向肿瘤相关巨噬细胞的致瘤性重编程：转录、表观遗传和代谢基础
Cancers (Basel). 2023 Aug 28;15(17):4291. doi: 10.3390/cancers15174291.
2
Transcriptional, Epigenetic and Metabolic Programming of Tumor-Associated Macrophages.肿瘤相关巨噬细胞的转录、表观遗传和代谢重编程
Cancers (Basel). 2020 May 29;12(6):1411. doi: 10.3390/cancers12061411.
3
Epigenetic Modifications in Tumor-Associated Macrophages: A New Perspective for an Old Foe.肿瘤相关巨噬细胞中的表观遗传修饰：老对手的新视角。
Front Immunol. 2022 Jan 24;13:836223. doi: 10.3389/fimmu.2022.836223. eCollection 2022.
4
Metabolic reprograming of MDSCs within tumor microenvironment and targeting for cancer immunotherapy.肿瘤微环境中 MDSCs 的代谢重编程及其在癌症免疫治疗中的靶向作用。
Acta Pharmacol Sin. 2022 Jun;43(6):1337-1348. doi: 10.1038/s41401-021-00776-4. Epub 2021 Sep 24.
5
Metabolic Switch in the Tumor Microenvironment Determines Immune Responses to Anti-cancer Therapy.肿瘤微环境中的代谢转换决定了对抗癌治疗的免疫反应。
Front Oncol. 2018 Aug 13;8:284. doi: 10.3389/fonc.2018.00284. eCollection 2018.
6
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression.肿瘤微环境中肿瘤相关巨噬细胞的免疫代谢特性和与线粒体相关的信号转导调节肿瘤的进展。
Biochem Pharmacol. 2023 Feb;208:115369. doi: 10.1016/j.bcp.2022.115369. Epub 2022 Dec 5.
7
Perspectives on reprograming cancer-associated dendritic cells for anti-tumor therapies.重编程癌症相关树突状细胞用于抗肿瘤治疗的前景。
Front Oncol. 2014 Apr 7;4:72. doi: 10.3389/fonc.2014.00072. eCollection 2014.
8
Inflammatory Components of the Thyroid Cancer Microenvironment: An Avenue for Identification of Novel Biomarkers.甲状腺癌微环境中的炎症成分：鉴定新型生物标志物的途径。
Adv Exp Med Biol. 2021;1350:1-31. doi: 10.1007/978-3-030-83282-7_1.
9
Epigenetic control of macrophage polarization: implications for targeting tumor-associated macrophages.巨噬细胞极化的表观遗传调控：对靶向肿瘤相关巨噬细胞的意义
Oncotarget. 2018 Feb 21;9(29):20908-20927. doi: 10.18632/oncotarget.24556. eCollection 2018 Apr 17.
10
The role of metabolic reprogramming of tumor-associated macrophages in shaping the immunosuppressive tumor microenvironment.肿瘤相关巨噬细胞的代谢重编程在塑造免疫抑制性肿瘤微环境中的作用。
Biomed Pharmacother. 2023 May;161:114504. doi: 10.1016/j.biopha.2023.114504. Epub 2023 Mar 14.
本文引用的文献
1
Advancements in understanding the role of microRnas in regulating macrophage polarization during acute lung injury.深入了解 microRnas 在调节急性肺损伤期间巨噬细胞极化中的作用的进展。
Cell Cycle. 2023 Jul-Aug;22(14-16):1694-1712. doi: 10.1080/15384101.2023.2230018. Epub 2023 Jul 6.
2
Exosomal miRNAs-mediated macrophage polarization and its potential clinical application.外泌体 miRNAs 介导的巨噬细胞极化及其潜在的临床应用。
Int Immunopharmacol. 2023 Apr;117:109905. doi: 10.1016/j.intimp.2023.109905. Epub 2023 Feb 27.
3
Guest Edited Collection: Epigenetics within the tumor microenvironment.客座编辑专刊：肿瘤微环境中的表观遗传学。
Sci Rep. 2022 Sep 5;12(1):15089. doi: 10.1038/s41598-022-19042-6.
4
Epigenetic regulation of immunosuppressive tumor-associated macrophages through dysregulated microRNAs.通过失调的微小RNA对免疫抑制性肿瘤相关巨噬细胞进行表观遗传调控。
Semin Cell Dev Biol. 2022 Apr;124:26-33. doi: 10.1016/j.semcdb.2021.09.001. Epub 2021 Sep 21.
5
Targeting macrophages in cancer immunotherapy.癌症免疫治疗中的靶向巨噬细胞。
Signal Transduct Target Ther. 2021 Mar 26;6(1):127. doi: 10.1038/s41392-021-00506-6.
6
Function of Macrophages in Disease: Current Understanding on Molecular Mechanisms.巨噬细胞在疾病中的功能：分子机制的现有理解。
Front Immunol. 2021 Mar 8;12:620510. doi: 10.3389/fimmu.2021.620510. eCollection 2021.
7
Transcriptional, Epigenetic and Metabolic Programming of Tumor-Associated Macrophages.肿瘤相关巨噬细胞的转录、表观遗传和代谢重编程
Cancers (Basel). 2020 May 29;12(6):1411. doi: 10.3390/cancers12061411.
8
Hypoxia modifies the polarization of macrophages and their inflammatory microenvironment, and inhibits malignant behavior in cancer cells.缺氧会改变巨噬细胞的极化及其炎症微环境，并抑制癌细胞的恶性行为。
Oncol Lett. 2019 Dec;18(6):5871-5878. doi: 10.3892/ol.2019.10956. Epub 2019 Oct 3.
9
Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages.脂滴依赖性脂肪酸代谢控制肿瘤相关巨噬细胞的免疫抑制表型。
EMBO Mol Med. 2019 Nov 7;11(11):e10698. doi: 10.15252/emmm.201910698. Epub 2019 Oct 10.
10
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications.肿瘤相关巨噬细胞在肿瘤转移中的作用：生物学功能及临床治疗应用。
J Hematol Oncol. 2019 Jul 12;12(1):76. doi: 10.1186/s13045-019-0760-3.
Zotero 插件