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大肠杆菌病毒T1的发育:从宿主限制中逃脱。

Development of Escherichia coli virus T1: escape from host restriction.

作者信息

Wagner E F, Auer B, Schweiger M

出版信息

J Virol. 1979 Mar;29(3):1229-31. doi: 10.1128/JVI.29.3.1229-1231.1979.

Abstract

The bacterial virus T1 grows interchangeably on different Escherichia coli strains (C, B, and K). This implies that T1 has an efficient mechanism to overcome the host restriction barrier. The DNA of T1 was found to be methylated independently of the hosts. The percentage of N6-methyladenine varied from 1.6 to 1.8, and the 5-methylcytosine content varied from 0.1 to 0.4%. In contrast, the range in percentage of N6-methyladenine and 5-methylcytosine found in the hosts was 0.7 to 2.4 and 0.0 to 1.1, respectively.

摘要

细菌病毒T1可在不同的大肠杆菌菌株(C、B和K)上交替生长。这意味着T1具有一种有效的机制来克服宿主限制屏障。研究发现,T1的DNA甲基化与宿主无关。N6-甲基腺嘌呤的百分比在1.6%至1.8%之间,5-甲基胞嘧啶的含量在0.1%至0.4%之间。相比之下,在宿主中发现的N6-甲基腺嘌呤和5-甲基胞嘧啶的百分比范围分别为0.7%至2.4%和0.0%至1.1%。

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