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Development of Escherichia coli virus T1: escape from host restriction.大肠杆菌病毒T1的发育:从宿主限制中逃脱。
J Virol. 1979 Mar;29(3):1229-31. doi: 10.1128/JVI.29.3.1229-1231.1979.
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Distribution of N6-methyladenine in DNA of T2 phage and its host Escherichia coli B.N6-甲基腺嘌呤在T2噬菌体及其宿主大肠杆菌B的DNA中的分布。
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Isolation of a mutant of Escherichia coli defective in cytosine-specific deoxyribonucleic acid methylase activity and in partial protection of bacteriophage lambda against restriction by cells containing the N-3 drug-resistance factor.分离出一株大肠杆菌突变体,该突变体在胞嘧啶特异性脱氧核糖核酸甲基化酶活性方面存在缺陷,并且在部分程度上不能保护λ噬菌体免受含有N-3耐药因子的细胞的限制作用。
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Plasmid-controlled variation in the content of methylated bases in bacteriophage lambda deoxyribonucleic acid.质粒控制的噬菌体λ脱氧核糖核酸中甲基化碱基含量的变异
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ROLE OF METHYLATION IN HOST CONTROLLED MODIFICATION OF PHAGE T1.甲基化在宿主控制的噬菌体T1修饰中的作用
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On the structure of the glucosylated hydroxymethylcytosine nucleotides of coliphages T2, T4, and T6.关于大肠杆菌噬菌体T2、T4和T6的糖基化羟甲基胞嘧啶核苷酸的结构
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A radiation-sensitive mutant of Escherichia coli.大肠杆菌的一种辐射敏感突变体。
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Host specificity of DNA produced by Escherichia coli: bacterial mutations affecting the restriction and modification of DNA.大肠杆菌产生的DNA的宿主特异性:影响DNA限制与修饰的细菌突变
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The enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. IX. Deoxyribonucleic acid methylase in bacteriophage-infected Escherichia coli.核糖核酸和脱氧核糖核酸的酶促甲基化。IX. 噬菌体感染的大肠杆菌中的脱氧核糖核酸甲基酶。
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Control of gene expression in bacteriophage T7: transcriptional controls.噬菌体T7中的基因表达调控:转录调控
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大肠杆菌病毒T1的发育:从宿主限制中逃脱。

Development of Escherichia coli virus T1: escape from host restriction.

作者信息

Wagner E F, Auer B, Schweiger M

出版信息

J Virol. 1979 Mar;29(3):1229-31. doi: 10.1128/JVI.29.3.1229-1231.1979.

DOI:10.1128/JVI.29.3.1229-1231.1979
PMID:376871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC353285/
Abstract

The bacterial virus T1 grows interchangeably on different Escherichia coli strains (C, B, and K). This implies that T1 has an efficient mechanism to overcome the host restriction barrier. The DNA of T1 was found to be methylated independently of the hosts. The percentage of N6-methyladenine varied from 1.6 to 1.8, and the 5-methylcytosine content varied from 0.1 to 0.4%. In contrast, the range in percentage of N6-methyladenine and 5-methylcytosine found in the hosts was 0.7 to 2.4 and 0.0 to 1.1, respectively.

摘要

细菌病毒T1可在不同的大肠杆菌菌株(C、B和K)上交替生长。这意味着T1具有一种有效的机制来克服宿主限制屏障。研究发现,T1的DNA甲基化与宿主无关。N6-甲基腺嘌呤的百分比在1.6%至1.8%之间,5-甲基胞嘧啶的含量在0.1%至0.4%之间。相比之下,在宿主中发现的N6-甲基腺嘌呤和5-甲基胞嘧啶的百分比范围分别为0.7%至2.4%和0.0%至1.1%。