Song Yunhong, Wu Ranran, Wei Xinlei, Shi Ting, Li Yunjie, You Chun, Zhang Lingling, Zhu Zhiguang, Zhang Yiheng
Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
National Innovation Center for Synthetic Biotechnology, Tianjin 300308, China.
Sheng Wu Gong Cheng Xue Bao. 2022 Nov 25;38(11):4081-4100. doi: 10.13345/j.cjb.220587.
The development of green and low-carbon renewable energy systems has become an important international consensus. It is also an essential path for China to implement the dual-carbon strategy, ensure national energy security, and achieve sustainable development. This review introduces the theory of a new energy system based on electricity-hydrogen-carbohydrate (EHC) cycle, and highlights the biotransformations of carbohydrate/water-to-hydrogen, carbohydrate-to-electricity, and CO-to-carbohydrate powered by hydrogen- or electric-energy based on the synthetic enzymatic biosystems (ivSEB) developed by Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences in the past decade. We elaborate the design principle and the molecular basis of ivSEB, and further expand from the EHC cycle to biomanufacturing with starch as the feedstock. Combined with the latest research advances, we analyze and discuss advantages and disadvantages of ivSEB, prospect future directions, so as to promote the green, low-carbon and sustainable development of economy and society.
绿色低碳可再生能源系统的发展已成为重要的国际共识。这也是中国实施双碳战略、保障国家能源安全、实现可持续发展的必由之路。本文综述了基于电-氢-碳水化合物（EHC）循环的新能源系统理论，并重点介绍了中国科学院天津工业生物技术研究所在过去十年中基于合成酶生物系统（ivSEB）实现的碳水化合物/水制氢、碳水化合物制电以及氢能或电能驱动的CO制碳水化合物的生物转化过程。我们阐述了ivSEB的设计原理和分子基础，并进一步从EHC循环拓展到以淀粉为原料的生物制造。结合最新研究进展，分析讨论了ivSEB的优缺点，展望了未来发展方向，以推动经济社会绿色、低碳、可持续发展。
