Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
College of Art and Sciences, Washington University in St. Louis, St. Louis, MO, United States.
Front Endocrinol (Lausanne). 2023 Aug 31;14:1231520. doi: 10.3389/fendo.2023.1231520. eCollection 2023.
Chronic inflammation and fibrosis are significant factors in the pathogenesis of metabolic-associated fatty liver disease (MAFLD). In this study, we conducted a bibliometric analysis of publications on inflammation and fibrogenesis in MAFLD, with a focus on reporting publication trends. Our findings indicate that the USA and China are the most productive countries in the field, with the University of California San Diego being the most productive institution. Over the past 23 years, Prof. Diehl AM has published 25 articles that significantly contributed to the research community. Notably, the research focus of the field has shifted from morbid obesity and adiponectin to metabolic syndrome, genetics, and microbiome. Our study provides a comprehensive and objective summary of the historical characteristics of research on inflammation and fibrogenesis in MAFLD, which will be of interest to scientific researchers in this field.
慢性炎症和纤维化是代谢相关脂肪性肝病（MAFLD）发病机制中的重要因素。在这项研究中，我们对 MAFLD 炎症和纤维化相关出版物进行了文献计量学分析，重点报告了发表趋势。我们的研究结果表明，美国和中国是该领域最具成果的国家，加利福尼亚大学圣地亚哥分校是最具成果的机构。在过去的 23 年中，Diehl AM 教授发表了 25 篇文章，为该研究领域做出了重要贡献。值得注意的是，该领域的研究重点已经从病态肥胖和脂联素转移到代谢综合征、遗传学和微生物组。本研究全面客观地总结了 MAFLD 炎症和纤维化研究的历史特征，这将引起该领域科学研究人员的兴趣。
