• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Patient with Epilepsy Showing Psychiatric Symptoms after Remission of Seizures and Normalization of Electroencephalography: The Phenomenon of Forced Normalization?

作者信息

Lee Hyoung Cheol, Kim Byung-Kun, Kang Kyusik, Lee Woong-Woo, Yoo Ilhan, Kim Yong Soo, Lee Jung-Ju

机构信息

Department of Neurology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.

出版信息

J Epilepsy Res. 2023 Jun 30;13(1):19-21. doi: 10.14581/jer.23004.

DOI:10.14581/jer.23004
PMID:37720682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10501814/
Abstract

Psychiatric disorders are commonly observed in patients with epilepsy. Among them, the phenomenon known as forced normalization is scarce. Herein, we report the case of a 41-year-old patient who showed long-term first-onset psychiatric symptoms after seizure remission and normalization of electroencephalography. After changing the antiepileptic drug regimen and psychiatric treatment, the patient's symptoms regressed. However, the exact pathological mechanisms remain to be elucidated. Changing the regimen of antiepileptic drugs and long-term psychiatric treatment may help control this phenomenon.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c768/10501814/a321f09226a6/jer-23004f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c768/10501814/a321f09226a6/jer-23004f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c768/10501814/a321f09226a6/jer-23004f1.jpg

相似文献

1
Patient with Epilepsy Showing Psychiatric Symptoms after Remission of Seizures and Normalization of Electroencephalography: The Phenomenon of Forced Normalization?
J Epilepsy Res. 2023 Jun 30;13(1):19-21. doi: 10.14581/jer.23004.
2
Forced normalization: case series from a Spanish epilepsy unit.强制性正常化:来自西班牙癫痫科的病例系列。
Seizure. 2020 Oct;81:132-137. doi: 10.1016/j.seizure.2020.07.020. Epub 2020 Jul 31.
3
Forced normalization after turning off vagus nerve stimulation in Lennox-Gastaut syndrome.Lennox-Gastaut综合征中迷走神经刺激关闭后的强制正常化
Epilepsy Behav Case Rep. 2019 Jan 27;11:81-83. doi: 10.1016/j.ebcr.2019.01.004. eCollection 2019.
4
Forced Normalization: Antagonism Between Epilepsy and Psychosis.强制正常化:癫痫与精神病之间的拮抗作用
Pediatr Neurol. 2017 May;70:16-19. doi: 10.1016/j.pediatrneurol.2017.02.007. Epub 2017 Feb 20.
5
De novo psychosis after left temporal lobectomy: a case of forced normalization?左颞叶切除术后新发精神病:一种强制正常化的情况?
Epileptic Disord. 2022 Feb 1;24(1):191-196. doi: 10.1684/epd.2021.1380.
6
Phenytoin Augmentation of Levetiracetam Treatment: A Case of Forced Normalization With Emergence of Psychosis.苯妥英增强左乙拉西坦治疗:一例出现精神病性症状的强制正常化病例。
Cureus. 2018 Apr 5;10(4):e2432. doi: 10.7759/cureus.2432.
7
A Girl with Idiopathic Epilepsy Showing Forced Normalization after Levetiracetam Administration.一名患有特发性癫痫的女孩在服用左乙拉西坦后出现强制性正常化。
J Nippon Med Sch. 2015;82(5):250-3. doi: 10.1272/jnms.82.250.
8
[Alternative Psychoses and Forced Normalization after Seizure Control by Anticonvulsants with Special Consideration of the New Anticonvulsants].[替代精神病及抗惊厥药物控制癫痫发作后的强制正常化,特别考虑新型抗惊厥药物]
Fortschr Neurol Psychiatr. 2020 May;88(5):307-317. doi: 10.1055/a-0820-3345. Epub 2019 Feb 20.
9
Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis.在无癫痫发作的患者中停用抗癫痫药物后癫痫复发和长期结局的个体化预测模型:系统评价和个体参与者数据荟萃分析。
Lancet Neurol. 2017 Jul;16(7):523-531. doi: 10.1016/S1474-4422(17)30114-X. Epub 2017 May 5.
10
Major Psychiatric Disorders Subsequent to Treating Epilepsy by Vagus Nerve Stimulation.迷走神经刺激治疗癫痫后出现的主要精神障碍
Epilepsy Behav. 2001 Oct;2(5):466-472. doi: 10.1006/ebeh.2001.0249.

本文引用的文献

1
Psychiatric comorbidities in epilepsy.癫痫共病的精神障碍。
Int Rev Psychiatry. 2017 Oct;29(5):409-424. doi: 10.1080/09540261.2017.1302412. Epub 2017 Jul 6.
2
Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process.左乙拉西坦治疗下的非癫痫性发作:强制性正常化过程的病例报告。
Neuropsychiatr Dis Treat. 2014 May 23;10:959-64. doi: 10.2147/NDT.S60089. eCollection 2014.
3
Psychosis in epilepsy patients.癫痫患者的精神病
Epilepsia. 2007;48 Suppl 9:17-9. doi: 10.1111/j.1528-1167.2007.01394.x.
4
Are psychiatric adverse events of antiepileptic drugs a unique entity? A study on topiramate and levetiracetam.抗癫痫药物的精神科不良事件是一种独特的情况吗?一项关于托吡酯和左乙拉西坦的研究。
Epilepsia. 2007 Dec;48(12):2322-6. doi: 10.1111/j.1528-1167.2007.01262.x. Epub 2007 Aug 17.
5
Psychiatric comorbidity in epilepsy: a population-based analysis.癫痫中的精神疾病共病:一项基于人群的分析。
Epilepsia. 2007 Dec;48(12):2336-44. doi: 10.1111/j.1528-1167.2007.01222.x. Epub 2007 Jul 28.
6
Forced normalization at the interface between epilepsy and psychiatry.癫痫与精神病学交界处的强制正常化。
Epilepsy Behav. 2002 Aug;3(4):303-308. doi: 10.1016/s1525-5050(02)00052-5.
7
Forced normalization: clinical and therapeutic relevance.强制正常化:临床及治疗相关性。
Epilepsia. 1999;40 Suppl 10:S57-64. doi: 10.1111/j.1528-1157.1999.tb00886.x.
8
Paradoxical normalization in childhood epilepsy.
Epilepsia. 1994 Sep-Oct;35(5):1060-4. doi: 10.1111/j.1528-1157.1994.tb02555.x.
9
Models for understanding the antagonism between seizures and psychosis.理解癫痫发作与精神病之间拮抗作用的模型。
Prog Neuropsychopharmacol Biol Psychiatry. 1987;11(4):483-504. doi: 10.1016/0278-5846(87)90017-0.
10
Acute behavioral symptomatology at disappearance of epileptiform EEG abnormality. Paradoxical or "forced" normalization.癫痫样脑电图异常消失时的急性行为症状学。矛盾性或“强制性”正常化。
Adv Neurol. 1991;55:127-42.