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On-chip physiological mimicry of neurovascular unit: challenges and perspectives.

作者信息

Ahn Song Ih, Kim YongTae

机构信息

School of Mechanical Engineering, Pusan National University, Busan, South Korea.

George W. Woodruff School of Mechanical Engineering; Parker H. Petit Institute for Bioengineering and Bioscience; Wallace H. Coulter Department of Biomedical Engineering; Institute for Electronics and Nanotechnology, Georgia Institute of Technology, Atlanta, GA, USA.

出版信息

Neural Regen Res. 2024 Mar;19(3):499-500. doi: 10.4103/1673-5374.380892.

DOI:10.4103/1673-5374.380892
PMID:37721272
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10581582/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2541/10581582/b2659cbc6152/NRR-19-499-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2541/10581582/b2659cbc6152/NRR-19-499-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2541/10581582/b2659cbc6152/NRR-19-499-g001.jpg

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Hyperglycemic Neurovasculature-On-A-Chip to Study the Effect of SIRT1-Targeted Therapy for the Type 3 Diabetes "Alzheimer's Disease".高血糖神经血管芯片研究 SIRT1 靶向治疗 3 型糖尿病“阿尔茨海默病”的作用
Adv Sci (Weinh). 2022 Dec;9(34):e2201882. doi: 10.1002/advs.202201882. Epub 2022 Sep 8.
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A microengineered Brain-Chip to model neuroinflammation in humans.
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iScience. 2022 Jul 21;25(8):104813. doi: 10.1016/j.isci.2022.104813. eCollection 2022 Aug 19.
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Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption.在人脑芯片中模拟α-突触核蛋白病理学,以评估血脑屏障的破坏。
Nat Commun. 2021 Oct 8;12(1):5907. doi: 10.1038/s41467-021-26066-5.
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