Kabzhanova Anar M, Kadyrov Ablaikhan S, Mukhanbetkaliyeva Aizada A, Yessembekova Gulzhan N, Mukhanbetkaliyev Yersin Y, Korennoy Fedor I, Perez Andres M, Abdrakhmanov Sarsenbay K
Faculty of Veterinary and Livestock Technology, S. Seifullin Kazakh Agro Technical Research University, Astana, Kazakhstan.
Federal Centre for Animal Health (FGBI ARRIAH), Vladimir, Russia.
Front Vet Sci. 2023 Sep 5;10:1252265. doi: 10.3389/fvets.2023.1252265. eCollection 2023.
Rabies is a fatal zoonotic disease that remains endemic in Kazakhstan despite the implementation of annual vaccination campaigns. Using data collected over a 10-year time period, the objective of this study was to provide updated information on the epidemiological situation of the disease in the country, and quantitative data on the species-specific spatial distribution of rabies and on the epidemiological features associated with that clustering. Five significant ( < 0.05) clusters of disease were detected. Clusters in southern Kazakhstan were associated with companion animals, which are likely explained by the maintenance of a domestic cycle of the disease in the most densely populated region of the country. Livestock cases were most frequent in clusters in the eastern (where wildlife cases were also frequent) and western regions of Kazakhstan, with higher probability of occurrence in spring and summer, compared to the rest of the year. The results here are consistent with differential patterns for disease transmission in Kazakhstan and will contribute to the design and implementation of zoning approaches to support the progressive control of rabies in the country.
狂犬病是一种致命的人畜共患病，尽管哈萨克斯坦每年都开展疫苗接种运动，但该病在该国仍然流行。本研究利用10年期间收集的数据，旨在提供该国该疾病流行病学情况的最新信息，以及狂犬病物种特异性空间分布和与该聚集相关的流行病学特征的定量数据。检测到5个显著（<0.05）的疾病聚集区。哈萨克斯坦南部的聚集区与伴侣动物有关，这可能是由于该国人口最密集地区存在该病的家庭传播循环。哈萨克斯坦东部（野生动物病例也很频繁）和西部地区的聚集区中家畜病例最为常见，与一年中的其他时间相比，春季和夏季发病概率更高。这里的结果与哈萨克斯坦疾病传播的不同模式一致，并将有助于设计和实施分区方法，以支持该国逐步控制狂犬病。
