Alqaidy Doaa
Department of Pathology, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Diagnostics (Basel). 2023 Sep 18;13(18):2982. doi: 10.3390/diagnostics13182982.
Thymomas are considered one of the most prevalent types of mediastinal epithelial tumors, which frequently develop in the anterior mediastinum. Due to their rarity, these tumors' nomenclature, classification, and staging are likely to be the subject of debate and argument for most expert pathologists. Furthermore, the significance of thymoma histologic classifications have been debated over the past twenty years. While certain advocates argue that staging at the time of diagnosis is more significant, others believe that histologic subtyping has a significant impact on how patients behave clinically. In this review, we will focus on some of the challenges that diagnostic surgical pathologists may experience while evaluating the histopathology of thymomas and staging these tumors. We will additionally glance over the clinical characteristics of these distinct tumors and the current management strategy.
胸腺瘤被认为是纵隔上皮性肿瘤中最常见的类型之一,常发生于前纵隔。由于其罕见性,这些肿瘤的命名、分类和分期很可能成为大多数专家病理学家争论的话题。此外,胸腺瘤组织学分类的意义在过去二十年中一直存在争议。虽然一些支持者认为诊断时的分期更重要,但另一些人则认为组织学亚型对患者的临床行为有重大影响。在本综述中,我们将重点关注诊断性外科病理学家在评估胸腺瘤组织病理学和对这些肿瘤进行分期时可能遇到的一些挑战。我们还将简要介绍这些独特肿瘤的临床特征和当前的管理策略。