Kim Hyun-Bae, Seo Myong-Won, Jung Hyun Chul
Department of Korean Sports Medicine, Daegu Haany University, Gyeongsan-si 38610, Gyengsanbuk-do, Republic of Korea.
Departments of Exercise Science, David B. Falk College of Sport and Human Dynamics, Syracuse University, Syracuse, NY 13244, USA.
Healthcare (Basel). 2023 Sep 7;11(18):2479. doi: 10.3390/healthcare11182479.
This study aimed to investigate the effects of different types of exercise (aerobic vs. resistance) on vascular function and vascular endothelial growth factor in older women. Forty-three older women, aged 65-75 years old, voluntarily participated in this study. All participants were randomly assigned to one of the following three groups: aerobic exercise (AE; = 14), resistance exercise (RE; = 15), and control (CG; = 14) groups. All participants in the exercise groups performed their respective exercises for 60 min/day, three days/week, for 16 weeks. The intensity of aerobic and resistance exercises was determined using the individual heart rate reserve (40-60%) and RPE (12-13), respectively. The vascular function test included the brachial-ankle pulse wave velocity (ba-PWV), carotid artery blood flow volume, and velocity. Participants' blood samples were collected to analyze the vascular endothelial growth factor (VEGF). A significance level of 0.05 was set. Our results showed that ba-PWV improved following both AE (14.5%) and RE groups (11.1%) (all < 0.05). Increases in carotid blood flow volume (AE: 15.4%, RE: 18.6%) and total artery peak velocity (AE: 20.4%, RE: 17%) were observed in AE and RE groups ( < 0.05), while flow total artery mean velocity (36.2%) and peak velocities (20.5%) were only increased in the aerobic exercise group ( < 0.05). VEGF was increased after resistance exercise ( < 0.05). Overall, aerobic exercise provides greater benefits on vascular function than resistance exercise but further research is needed on VEGF regarding whether this change is associated with vascular function improvement in older women.
本研究旨在探讨不同类型运动（有氧运动与抗阻运动）对老年女性血管功能和血管内皮生长因子的影响。43名年龄在65至75岁之间的老年女性自愿参与了本研究。所有参与者被随机分配到以下三组之一：有氧运动组（AE；n = 14）、抗阻运动组（RE；n = 15）和对照组（CG；n = 14）。运动组的所有参与者每天进行各自的运动60分钟，每周三天，共16周。有氧运动和抗阻运动的强度分别使用个体心率储备（40 - 60%）和主观用力程度分级（12 - 13）来确定。血管功能测试包括肱踝脉搏波速度（ba - PWV）、颈动脉血流量和流速。采集参与者的血样以分析血管内皮生长因子（VEGF）。设定显著性水平为0.05。我们的结果显示，有氧运动组（14.5%）和抗阻运动组（11.1%）的ba - PWV均有所改善（均P < 0.05）。有氧运动组和抗阻运动组的颈动脉血流量增加（有氧运动组：15.4%，抗阻运动组：18.6%）以及总动脉峰值流速增加（有氧运动组：20.4%，抗阻运动组：17%）（P < 0.05），而总动脉平均流速（36.2%）和峰值流速（20.5%）仅在有氧运动组增加（P < 0.05）。抗阻运动后VEGF增加（P < 0.05）。总体而言，有氧运动对血管功能的益处大于抗阻运动，但关于VEGF，是否这种变化与老年女性血管功能改善相关还需要进一步研究。
